cIMPACT-NOW update 3: recommended diagnostic criteria for “Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV”
The World Health Organization (WHO) central nervous system tumor classification
represents the primary source of updates on diagnostic classes, grades and criteria [17] …
represents the primary source of updates on diagnostic classes, grades and criteria [17] …
Reconstructing the molecular life history of gliomas
At the time of their clinical manifestation, the heterogeneous group of adult and pediatric
gliomas carries a wide range of diverse somatic genomic alterations, ranging from somatic …
gliomas carries a wide range of diverse somatic genomic alterations, ranging from somatic …
Distribution of EGFR amplification, combined chromosome 7 gain and chromosome 10 loss, and TERT promoter mutation in brain tumors and their potential for the …
EGFR amplification (EGFR amp), the combination of gain of chromosome 7 and loss of
chromosome 10 (7+/10−), and TERT promoter mutation (p TERT mut) are alterations …
chromosome 10 (7+/10−), and TERT promoter mutation (p TERT mut) are alterations …
Clinical impact of revisions to the WHO classification of diffuse gliomas and associated future problems
Y Sonoda - International Journal of Clinical Oncology, 2020 - Springer
The publication of the 2016 World Health Organization Classification of Tumors of the
Central Nervous System (2016 WHO CNS) represented a major change in the classification …
Central Nervous System (2016 WHO CNS) represented a major change in the classification …
Telomerase in differentiated thyroid cancer: promoter mutations, expression and localization
M Muzza, C Colombo, S Rossi, D Tosi, V Cirello… - Molecular and cellular …, 2015 - Elsevier
Abstract Telomerase-reverse-transcriptase (TERT) promoter mutations have been recently
described in tumors. In the present large series, TERT mutations were found in 12% of …
described in tumors. In the present large series, TERT mutations were found in 12% of …
Prognostic implication of TERT promoter mutation and circulating tumor cells in muscle-invasive bladder cancer
R Carrasco, M Ingelmo-Torres, A Gómez… - World Journal of …, 2022 - Springer
Purpose Current clinical prognostic factors are not accurate enough to identify and monitor
those muscle-invasive bladder cancer (MIBC) patients at high risk of progression after …
those muscle-invasive bladder cancer (MIBC) patients at high risk of progression after …
TERT promoter mutation and chromosome 6 loss define a high-risk subtype of ependymoma evolving from posterior fossa subependymoma
C Thomas, F Thierfelder, M Träger, P Soschinski… - Acta …, 2021 - Springer
Subependymomas are benign tumors characteristically encountered in the posterior fossa of
adults that show distinct epigenetic profiles assigned to the molecular group …
adults that show distinct epigenetic profiles assigned to the molecular group …
HDAC inhibition induces PD-L1 expression in a novel anaplastic thyroid cancer cell line
While papillary thyroid cancer (PTC) has largely favorable prognosis, anaplastic thyroid
cancer (ATC) is a rare but extremely aggressive malignancy with grim clinical outcome …
cancer (ATC) is a rare but extremely aggressive malignancy with grim clinical outcome …
Association of clinicopathological features and prognosis of TERT alterations in phyllodes tumor of breast
JYS Tsang, YK Hui, MA Lee, M Lacambra, YB Ni… - Scientific reports, 2018 - nature.com
Phyllodes tumor (PT) of the breast is a rare but clinically important fibroepithelial tumor with
potential risks of recurrence and metastasis. Recent studies identified recurrent TERT …
potential risks of recurrence and metastasis. Recent studies identified recurrent TERT …
The TERT Promoter: A Key Player in the Fight for Cancer Cell Immortality
TN Hasanau, EP Pisarev, OV Kisil, ME Zvereva - Biochemistry (Moscow), 2023 - Springer
The review describes the role of telomeres and telomerase in tumor progression, as well as
various mechanisms of the activation of telomerase reverse transcriptase (TERT) expression …
various mechanisms of the activation of telomerase reverse transcriptase (TERT) expression …