[HTML][HTML] miRNA-based biomarkers, therapies, and resistance in Cancer

B He, Z Zhao, Q Cai, Y Zhang, P Zhang… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
Abstract MicroRNAs (miRNAs), small non-coding RNAs (ncRNAs) of about 22 nucleotides in
size, play important roles in gene regulation, and their dysregulation is implicated in human …

Extracellular vesicles in cancer—implications for future improvements in cancer care

R Xu, A Rai, M Chen, W Suwakulsiri… - Nature reviews Clinical …, 2018 - nature.com
The sustained growth, invasion, and metastasis of cancer cells depend upon bidirectional
cell–cell communication within complex tissue environments. Such communication …

The HPV E6/E7 oncogenes: key factors for viral carcinogenesis and therapeutic targets

K Hoppe-Seyler, F Bossler, JA Braun, AL Herrmann… - Trends in …, 2018 - cell.com
Human papillomavirus (HPV)-induced cancers are expected to remain a major health
problem worldwide for decades. The growth of HPV-positive cancer cells depends on the …

A current update on human papillomavirus-associated head and neck cancers

E Tumban - Viruses, 2019 - mdpi.com
Human papillomavirus (HPV) infection is the cause of a growing percentage of head and
neck cancers (HNC); primarily, a subset of oral squamous cell carcinoma, oropharyngeal …

[HTML][HTML] Exosome biogenesis, regulation, and function in viral infection

M Alenquer, MJ Amorim - Viruses, 2015 - mdpi.com
Exosomes are extracellular vesicles released upon fusion of multivesicular bodies (MVBs)
with the cellular plasma membrane. They originate as intraluminal vesicles (ILVs) during the …

HPV16 and HPV18 genome structure, expression, and post-transcriptional regulation

L Yu, V Majerciak, ZM Zheng - International journal of molecular sciences, 2022 - mdpi.com
Human papillomaviruses (HPV) are a group of small non-enveloped DNA viruses whose
infection causes benign tumors or cancers. HPV16 and HPV18, the two most common high …

[HTML][HTML] Enhanced expression of PD L1 in cervical intraepithelial neoplasia and cervical cancers

L Mezache, B Paniccia, A Nyinawabera, GJ Nuovo - Modern Pathology, 2015 - Elsevier
Programmed death ligand 1 (PD L1) expression can reduce the immune response in both
infectious diseases and cancers. We thus examined PD L1 expression in cervical …

MicroRNAs as markers of progression in cervical cancer: a systematic review

B Pardini, D De Maria, A Francavilla, C Di Gaetano… - BMC cancer, 2018 - Springer
Background Invasive cervical cancer (ICC) is caused by high-risk human papillomavirus
types (HR-HPVs) and is usually preceded by a long phase of intraepithelial neoplasia (CIN) …

Dependence of Intracellular and Exosomal microRNAs on Viral E6/E7 Oncogene Expression in HPV-positive Tumor Cells

A Honegger, D Schilling, S Bastian, J Sponagel… - PLoS …, 2015 - journals.plos.org
Specific types of human papillomaviruses (HPVs) cause cervical cancer. Cervical cancers
exhibit aberrant cellular microRNA (miRNA) expression patterns. By genome-wide analyses …

The versatile role of exosomes in human retroviral infections: from immunopathogenesis to clinical application

J Rezaie, C Aslan, M Ahmadi, NM Zolbanin… - Cell & Bioscience, 2021 - Springer
Eukaryotic cells produce extracellular vesicles (EVs) mediating intercellular communication.
These vesicles encompass many bio-molecules such as proteins, nucleic acids, and lipids …