[HTML][HTML] The potential of using E. coli as an indicator for the surveillance of antimicrobial resistance (AMR) in the environment

MF Anjum, H Schmitt, S Börjesson… - Current Opinion in …, 2021 - Elsevier
Highlights•There is an urgent need for environmental Antimicrobial resistance (AMR)
monitoring.•E. coli are part of established human and livestock AMR surveillance …

[HTML][HTML] How do interactions between mobile genetic elements affect horizontal gene transfer?

T Horne, VT Orr, JPJ Hall - Current opinion in microbiology, 2023 - Elsevier
Highlights•Collaboration and conflict between MGEs can promote and inhibit HGT•Many
genome defences are MGE-encoded, serving MGE interests and changing frequently•The …

Assessment of global health risk of antibiotic resistance genes

Z Zhang, Q Zhang, T Wang, N Xu, T Lu, W Hong… - Nature …, 2022 - nature.com
Antibiotic resistance genes (ARGs) have accelerated microbial threats to human health in
the last decade. Many genes can confer resistance, but evaluating the relative health risks of …

Role of horizontal gene transfer in the dissemination of antimicrobial resistance in food animal production

PG Vinayamohan, AJ Pellissery… - Current Opinion in Food …, 2022 - Elsevier
Highlights•Microorganisms acquires antimicrobial resistance genes via horizontal gene
transfer.•Mobile genetic elements disseminate antimicrobial resistance genes in the food …

Comparison of R9. 4.1/Kit10 and R10/Kit12 Oxford Nanopore flowcells and chemistries in bacterial genome reconstruction

ND Sanderson, N Kapel, G Rodger… - Microbial …, 2023 - microbiologyresearch.org
Complete, accurate, cost-effective, and high-throughput reconstruction of bacterial genomes
for large-scale genomic epidemiological studies is currently only possible with hybrid …

Exploring gene content with pangene graphs

H Li, M Marin, MR Farhat - Bioinformatics, 2024 - academic.oup.com
Motivation The gene content regulates the biology of an organism. It varies between species
and between individuals of the same species. Although tools have been developed to …

Role of mobile genetic elements in the global dissemination of the carbapenem resistance gene blaNDM

M Acman, R Wang, L van Dorp, LP Shaw… - Nature …, 2022 - nature.com
The mobile resistance gene bla NDM encodes the NDM enzyme which hydrolyses
carbapenems, a class of antibiotics used to treat some of the most severe bacterial …

Microorganism microneedle micro-engine depth drug delivery

B Zheng, Q Li, L Fang, X Cai, Y Liu, Y Duo, B Li… - Nature …, 2024 - nature.com
As a transdermal drug delivery method, microneedles offer minimal invasiveness,
painlessness, and precise in-situ treatment. However, current microneedles rely on passive …

A role for ColV plasmids in the evolution of pathogenic Escherichia coli ST58

CJ Reid, ML Cummins, S Börjesson… - Nature …, 2022 - nature.com
Escherichia coli ST58 has recently emerged as a globally disseminated uropathogen that
often progresses to sepsis. Unlike most pandemic extra-intestinal pathogenic E. coli …

Microbial species and intraspecies units exist and are maintained by ecological cohesiveness coupled to high homologous recombination

RE Conrad, CE Brink, T Viver, LM Rodriguez-R… - Nature …, 2024 - nature.com
Recent genomic analyses have revealed that microbial communities are predominantly
composed of persistent, sequence-discrete species and intraspecies units (genomovars) …