ICU-acquired weakness

I Vanhorebeek, N Latronico, G Van den Berghe - Intensive care medicine, 2020 - Springer
Critically ill patients often acquire neuropathy and/or myopathy labeled ICU-acquired
weakness. The current insights into incidence, pathophysiology, diagnostic tools, risk …

COVID-19 and respiratory system disorders: current knowledge, future clinical and translational research questions

SB Brosnahan, AH Jonkman, MC Kugler… - … , and vascular biology, 2020 - ahajournals.org
The severe acute respiratory syndrome coronavirus-2 emerged as a serious human
pathogen in late 2019, causing the disease coronavirus disease 2019 (COVID-19). The …

[HTML][HTML] Clinical strategies for implementing lung and diaphragm-protective ventilation: avoiding insufficient and excessive effort

EC Goligher, AH Jonkman, J Dianti, K Vaporidi… - Intensive care …, 2020 - Springer
Mechanical ventilation may have adverse effects on both the lung and the diaphragm. Injury
to the lung is mediated by excessive mechanical stress and strain, whereas the diaphragm …

[HTML][HTML] Respiratory muscle ultrasonography: methodology, basic and advanced principles and clinical applications in ICU and ED patients—a narrative review

PR Tuinman, AH Jonkman, M Dres, ZH Shi… - Intensive care …, 2020 - Springer
Respiratory muscle ultrasound is used to evaluate the anatomy and function of the
respiratory muscle pump. It is a safe, repeatable, accurate, and non-invasive bedside …

[HTML][HTML] Patient-self inflicted lung injury: a practical review

G Carteaux, M Parfait, M Combet… - Journal of clinical …, 2021 - mdpi.com
Patients with severe lung injury usually have a high respiratory drive, resulting in intense
inspiratory effort that may even worsen lung damage by several mechanisms gathered …

Ultrasound and non-ultrasound imaging techniques in the assessment of diaphragmatic dysfunction

FA Laghi, M Saad, H Shaikh - BMC Pulmonary Medicine, 2021 - Springer
Diaphragm muscle dysfunction is increasingly recognized as an important element of
several diseases including neuromuscular disease, chronic obstructive pulmonary disease …

Multi-organ point-of-care ultrasound for COVID-19 (PoCUS4COVID): international expert consensus

A Hussain, G Via, L Melniker, A Goffi, G Tavazzi, L Neri… - Critical care, 2020 - Springer
COVID-19 has caused great devastation in the past year. Multi-organ point-of-care
ultrasound (PoCUS) including lung ultrasound (LUS) and focused cardiac ultrasound …

Effectiveness of diaphragmatic ultrasound as a predictor of successful weaning from mechanical ventilation: a systematic review and meta-analysis

HM Parada-Gereda, AL Tibaduiza, A Rico-Mendoza… - Critical Care, 2023 - Springer
Background Several measurements have been used to predict the success of weaning from
mechanical ventilation; however, their efficacy varies in different studies. In recent years …

Diaphragmatic myotrauma: a mediator of prolonged ventilation and poor patient outcomes in acute respiratory failure

EC Goligher, LJ Brochard, WD Reid, E Fan… - The Lancet …, 2019 - thelancet.com
Several mechanisms of diaphragm muscle injury (myotrauma) can result in ventilator-
induced diaphragm dysfunction, including ventilator over-assistance, under-assistance …

Diaphragm pathology in critically ill patients with COVID-19 and postmortem findings from 3 medical centers

Z Shi, HJ De Vries, APJ Vlaar… - JAMA internal …, 2021 - jamanetwork.com
Methods| Our study focused on the diaphragm, the main muscle of respiration. Consecutive
diaphragm muscle specimens were collected during autopsy from the corpses of 26 patients …