Studies of families and twins show the importance of genetic factors affecting susceptibility to
bipolar disorder and suggest substantial genetic and phenotypic complexity. Robust and …

Objective The primary objective of this review is to examine the literature assessing
abnormalities in neural circuitry and cognition early in the course of major depressive …

The complex nature of human cognition has resulted in cognitive genomics lagging behind
many other fields in terms of gene discovery using genome-wide association study (GWAS) …

Background Recent data suggest trait-like neurocognitive impairments in bipolar disorder
(BPD), with deficits about 1 sd below average, less severe than deficits noted in …

Background The neuropsychological correlates of major depressive (MDD) and bipolar
disorder (BD), and their association with quality of life (QOL) and functioning, have not been …

Cognitive functioning is moderately to severely impaired in patients with schizophrenia. This
impairment is the prime driver of the significant disabilities in occupational, social, and …

Objectives To aid the development of treatment for cognitive impairment in bipolar disorder,
the International Society for Bipolar Disorders (ISBD) convened a task force to create a …

Background Current group-average analysis suggests quantitative but not qualitative
cognitive differences between schizophrenia (SZ) and bipolar disorder (BD). There is …

Objective This study aimed to determine the relative extent of impairment in social and
nonsocial cognitive domains in patients with bipolar disorder compared with schizophrenia …

Bipolar disorder (BD) and major depressive disorder (MDD) are heritable neuropsychiatric
disorders associated with disrupted circadian rhythms. The hypothesis that circadian clock …