TRP channels

K Venkatachalam, C Montell - Annu. Rev. Biochem., 2007 - annualreviews.org
Abstract The TRP (Transient Receptor Potential) superfamily of cation channels is
remarkable in that it displays greater diversity in activation mechanisms and selectivities …

Cellular mechanotransduction: putting all the pieces together again

DE Ingber - The FASEB journal, 2006 - Wiley Online Library
Analysis of cellular mechanotransduction, the mechanism by which cells convert mechanical
signals into biochemical responses, has focused on identification of critical …

[BOOK][B] An introduction to the physiology of hearing

JO Pickles - 1988 - academia.edu
5. Mechanisms of Transduction and Excitation in the Cochlea.. 1 1 2 A. Introduction.......... 1 1
2 B. The cytoskeleton of the transducer region..... 1 1 3 C. Mechanisms of transduction....... 1 …

[HTML][HTML] TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents

DM Bautista, SE Jordt, T Nikai, PR Tsuruda, AJ Read… - Cell, 2006 - cell.com
TRPA1 is an excitatory ion channel targeted by pungent irritants from mustard and garlic.
TRPA1 has been proposed to function in diverse sensory processes, including thermal …

[PDF][PDF] An introduction to TRP channels

IS Ramsey, M Delling, DE Clapham - Annual review of …, 2006 - researchgate.net
AN INTRODUCTION TO TRP CHANNELS Page 1 Annu. Rev. Physiol. 2006. 68:619–47 doi:
10.1146/annurev.physiol.68.040204.100431 Copyright cO 2006 by Annual Reviews. All rights …

Transient receptor potential cation channels in disease

B Nilius, G Owsianik, T Voets… - Physiological …, 2007 - journals.physiology.org
The transient receptor potential (TRP) superfamily consists of a large number of cation
channels that are mostly permeable to both monovalent and divalent cations. The 28 …

[HTML][HTML] Mammalian transient receptor potential TRPA1 channels: from structure to disease

K Talavera, JB Startek, J Alvarez-Collazo… - Physiological …, 2020 - journals.physiology.org
The transient receptor potential ankyrin (TRPA) channels are Ca 2+-permeable nonselective
cation channels remarkably conserved through the animal kingdom. Mammals have only …

TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction

KY Kwan, AJ Allchorne, MA Vollrath, AP Christensen… - Neuron, 2006 - cell.com
TRPA1, a member of the transient receptor potential (TRP) family of ion channels, is
expressed by dorsal root ganglion neurons and by cells of the inner ear, where it has …

The TRP superfamily of cation channels

C Montell - Science's STKE, 2005 - science.org
The transient receptor potential (TRP) protein superfamily consists of a diverse group of
cation channels that bear structural similarities to Drosophila TRP. TRP channels play …

Transient receptor potential channels as drug targets: from the science of basic research to the art of medicine

B Nilius, A Szallasi - Pharmacological reviews, 2014 - Elsevier
The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …