Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options

CR Lee, JH Lee, M Park, KS Park, IK Bae… - Frontiers in cellular …, 2017 - frontiersin.org
Acinetobacter baumannii is undoubtedly one of the most successful pathogens responsible
for hospital-acquired nosocomial infections in the modern healthcare system. Due to the …

The Mechanisms of Disease Caused by Acinetobacter baumannii

FC Morris, C Dexter, X Kostoulias, MI Uddin… - Frontiers in …, 2019 - frontiersin.org
Acinetobacter baumannii is a Gram negative opportunistic pathogen that has demonstrated
a significant insurgence in the prevalence of infections over recent decades. With only a …

Neutrophil extracellular traps (NETs) and damage‐associated molecular patterns (DAMPs): two potential targets for COVID‐19 treatment

S Cicco, G Cicco, V Racanelli… - Mediators of …, 2020 - Wiley Online Library
COVID‐19 is a pandemic disease caused by the new coronavirus SARS‐CoV‐2 that mostly
affects the respiratory system. The consequent inflammation is not able to clear viruses. The …

Convergence of Biofilm Formation and Antibiotic Resistance in Acinetobacter baumannii Infection

S Roy, G Chowdhury, AK Mukhopadhyay… - Frontiers in …, 2022 - frontiersin.org
Acinetobacter baumannii (A. baumannii) is a leading cause of nosocomial infections as this
pathogen has certain attributes that facilitate the subversion of natural defenses of the …

Effects of antibiotics upon the gut microbiome: a review of the literature

T Konstantinidis, C Tsigalou, A Karvelas… - Biomedicines, 2020 - mdpi.com
The human gastrointestinal tract carries a large number of microorganisms associated with
complex metabolic processes and interactions. Although antibiotic treatment is crucial for …

Neutrophils and neutrophil extracellular traps in the liver and gastrointestinal system

M Honda, P Kubes - Nature reviews Gastroenterology & hepatology, 2018 - nature.com
Neutrophil extracellular traps (NETs) have an important role during infection by hel**
neutrophils to capture and kill pathogens. However, evidence is accumulating that …

Phagocytosis, degranulation and extracellular traps release by neutrophils—the current knowledge, pharmacological modulation and future prospects

B Gierlikowska, A Stachura, W Gierlikowski… - Frontiers in …, 2021 - frontiersin.org
Neutrophils are crucial elements of innate immune system, which assure host defense via a
range of effector functions, such as phagocytosis, degranulation, and NET formation. The …

The immunomodulatory effects of macrolide antibiotics in respiratory disease

J Pollock, JD Chalmers - Pulmonary Pharmacology & Therapeutics, 2021 - Elsevier
Macrolide antibiotics are well known for their antibacterial properties, but extensive research
in the context of inflammatory lung disease has revealed that they also have powerful …

In vitro induction of NETosis: Comprehensive live imaging comparison and systematic review

T Hoppenbrouwers, ASA Autar, AR Sultan… - PloS one, 2017 - journals.plos.org
Background Multiple inducers of in vitro Neutrophil Extracellular Trap (NET) formation
(NETosis) have been described. Since there is much variation in study design and results …

Neutrophil autophagy and extracellular DNA traps contribute to airway inflammation in severe asthma

DL Pham, GY Ban, SH Kim, YS Shin… - Clinical & …, 2017 - Wiley Online Library
Background Autophagy and neutrophil extracellular DNA traps (NET s) are implicated in
asthma; however, their roles in asthma pathogenesis have not been elucidated. Objectives …