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Integration of substrate-and flow-derived stresses in endothelial cell mechanobiology
Endothelial cells (ECs) lining all blood vessels are subjected to large mechanical stresses
that regulate their structure and function in health and disease. Here, we review EC …
that regulate their structure and function in health and disease. Here, we review EC …
Surface engineering of cardiovascular devices for improved hemocompatibility and rapid endothelialization
J Zhao, Y Feng - Advanced Healthcare Materials, 2020 - Wiley Online Library
Cardiovascular devices have been widely applied in the clinical treatment of cardiovascular
diseases. However, poor hemocompatibility and slow endothelialization on their surface still …
diseases. However, poor hemocompatibility and slow endothelialization on their surface still …
Improved cellular infiltration in electrospun fiber via engineered porosity
Small pore sizes inherent to electrospun matrices can hinder efficient cellular ingrowth. To
facilitate infiltration while retaining its extracellular matrix-like character, electrospinning was …
facilitate infiltration while retaining its extracellular matrix-like character, electrospinning was …
Cell‐perceived substrate curvature dynamically coordinates the direction, speed, and persistence of stromal cell migration
Adherent cells residing within tissues or biomaterials are presented with 3D geometrical
cues from their environment, often in the form of local surface curvatures. While there is …
cues from their environment, often in the form of local surface curvatures. While there is …
Construction of a bilayered vascular graft with smooth internal surface for improved hemocompatibility and endothelial cell monolayer formation
Formation of a continuous endothelial cell (EC) monolayer inside the luminal surface with
enhanced hemocompatibility, is a promising solution for improving performance and overall …
enhanced hemocompatibility, is a promising solution for improving performance and overall …
Mesoscale substrate curvature overrules nanoscale contact guidance to direct bone marrow stromal cell migration
M Werner, NA Kurniawan, G Korus… - Journal of The …, 2018 - royalsocietypublishing.org
The intrinsic architecture of biological tissues and of implanted biomaterials provides cells
with large-scale geometrical cues. To understand how cells are able to sense and respond …
with large-scale geometrical cues. To understand how cells are able to sense and respond …
Plasma-based nanostructuring of polymers: A review
There are various fabrication methods for synthesizing nanostructures, among which plasma-
based technology is strongly competitive in terms of its flexibility and friendly uses, economy …
based technology is strongly competitive in terms of its flexibility and friendly uses, economy …
Protein micropatterning in 2.5 D: an approach to investigate cellular responses in multi-cue environments
C van Der Putten, ABC Buskermolen… - … applied materials & …, 2021 - ACS Publications
The extracellular microenvironment is an important regulator of cell functions. Numerous
structural cues present in the cellular microenvironment, such as ligand distribution and …
structural cues present in the cellular microenvironment, such as ligand distribution and …
[HTML][HTML] Aligned fibrous scaffolds promote directional migration of breast cancer cells via caveolin-1/YAP-mediated mechanosensing
P Li, H Zhou, R Yan, W Yan, L Yang, T Li, X Qin… - Materials Today Bio, 2024 - Elsevier
Tumorigenesis and metastasis are highly dependent on the interactions between the tumor
and the surrounding microenvironment. In 3D matrix, the fibrous structure of the extracellular …
and the surrounding microenvironment. In 3D matrix, the fibrous structure of the extracellular …
Substrate curvature restricts spreading and induces differentiation of human mesenchymal stem cells
SJ Lee, S Yang - Biotechnology journal, 2017 - Wiley Online Library
While cells attach, spread, migrate, proliferate, and differentiate in three‐dimensional (3D)
micromechanical environments, the mechanical factors of these environments influence the …
micromechanical environments, the mechanical factors of these environments influence the …