Titanium (Ti) and its alloys have been widely used as orthopedic implants, because of their
favorable mechanical properties, corrosion resistance and biocompatibility. Despite their …

Living cells are constantly exposed to mechanical stimuli arising from the surrounding
extracellular matrix (ECM) or from neighboring cells. The intracellular molecular processes …

Toward the aim of personalized treatment, three-dimensional (3D) printing technology has
been widely used in bone tissue engineering owing to its advantage of a fast, precise, and …

Chronic non-healing wounds persist as a substantial burden for healthcare systems,
influenced by factors such as aging, diabetes, and obesity. In contrast to the traditionally pro …

Fibroblasts are cells present throughout the human body that are primarily responsible for
the production and maintenance of the extracellular matrix (ECM) within the tissues. They …

Evolution of metal implants progressively shifted the focus from adequate mechanical
strength to improved biocompatibility and absence of toxicity and, finally, to fast …

Although the biological functions of cell and tissue can be regulated by biochemical factors
(eg, growth factors, hormones), the biophysical effects of materials on the regulation of …

Biointerfaces mediate safe and efficient cell manipulation, which is essential for biomedical
innovations in advanced therapies and diagnostics. The biointerface established by vertical …

In 1991, Iijima reported on the formation of carbon nanotubes (1) using a simple arc
discharge reaction that led to an arrangement of the material in some micrometer long tubes …

Cells have evolved multiple mechanisms to apprehend and adapt finely to their
environment. Here we report a new cellular ability, which we term “curvotaxis” that enables …