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Liposomes in cancer therapy: how did we start and where are we now
MD Fulton, W Najahi-Missaoui - International Journal of Molecular …, 2023 - mdpi.com
Since their first discovery in the 1960s by Alec Bangham, liposomes have been shown to be
effective drug delivery systems for treating various cancers. Several liposome-based …
effective drug delivery systems for treating various cancers. Several liposome-based …
Application of light scattering techniques to nanoparticle characterization and development
Over the years, the scientific importance of nanoparticles for biomedical applications has
increased. The high stability and biocompatibility, together with the low toxicity of the …
increased. The high stability and biocompatibility, together with the low toxicity of the …
Non-viral delivery systems for CRISPR/Cas9-based genome editing: Challenges and opportunities
L Li, S Hu, X Chen - Biomaterials, 2018 - Elsevier
In recent years, CRISPR (clustered regularly interspaced short palindromic repeat)/Cas
(CRISPR-associated) genome editing systems have become one of the most robust …
(CRISPR-associated) genome editing systems have become one of the most robust …
Cleavable PEGylation: a strategy for overcoming the “PEG dilemma” in efficient drug delivery
Y Fang, J Xue, S Gao, A Lu, D Yang, H Jiang, Y He… - Drug Delivery, 2017 - Taylor & Francis
To prolong the circulation time of drug, PEGylation has been widely used via the enhanced
permeability and retention (EPR) effect, thereby providing new hope for better treatment …
permeability and retention (EPR) effect, thereby providing new hope for better treatment …
Cell penetrating peptides as molecular carriers for anti-cancer agents
Cell membranes with their selective permeability play important functions in the tight control
of molecular exchanges between the cytosol and the extracellular environment as the …
of molecular exchanges between the cytosol and the extracellular environment as the …
Ligand-targeted liposome design: challenges and fundamental considerations
Nanomedicine, particularly liposomal drug delivery, has expanded considerably over the
past few decades, and several liposomal drugs are already providing improved clinical …
past few decades, and several liposomal drugs are already providing improved clinical …
Cell-penetrating peptides: breaking through to the other side
Cell-penetrating peptides (CPPs) have been previously shown to be powerful transport
vector tools for the intracellular delivery of a large variety of cargoes through the cell …
vector tools for the intracellular delivery of a large variety of cargoes through the cell …
Stimulus-responsive liposomes for biomedical applications
Liposomes are amphipathic lipidic supramolecular aggregates that are able to encapsulate
and carry molecules of both hydrophilic and hydrophobic nature. They have been widely …
and carry molecules of both hydrophilic and hydrophobic nature. They have been widely …
[HTML][HTML] CRISPR/Cas9 gene editing: New hope for Alzheimer's disease therapeutics
Background Alzheimer's disease (AD) is an insidious, irreversible, and progressive
neurodegenerative health condition manifesting as cognitive deficits and amyloid beta (Aβ) …
neurodegenerative health condition manifesting as cognitive deficits and amyloid beta (Aβ) …
Effect of surface properties on liposomal siRNA delivery
Liposomes are one of the most widely investigated carriers for siRNA delivery. The surface
properties of liposomal carriers, including the surface charge, PEGylation, and ligand …
properties of liposomal carriers, including the surface charge, PEGylation, and ligand …