The concept of spatially fractionated radiation therapy (SFRT) was conceived over 100 years
ago, first in the form of GRID, which has been applied to clinical practice since its early …

Although the combination of immune checkpoint blockades with high dose of radiation has
indicated the potential of co-stimulatory effects, consistent clinical outcome has been yet to …

Purpose: Carcinogenic effects of radiation are often assumed to be universally understood,
more often than, for example, carcinogenic effects of many different chemicals. This in turn …

CD34+ cells improve the perfusion and function of ischemic limbs in humans and mice.
However, there is no direct evidence of the differentiation potential and functional role of …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of
the coronavirus disease 2019 (COVID-19), has caused more than 179 million infections and …

Critical limb ischemia (CLI) is the most severe clinical manifestation of peripheral arterial
disease, which causes many amputations and deaths. Conventional treatment strategies for …

Background: Assessment of tissue perfusion after irradiation of random pattern flaps still
remains a challenge. Methods: Twenty-five rats received harvesting of bilateral random …

This study aimed to develop a novel and non-invasive approach, low-dose radiation (LDR,
75 mGy X-rays), to prevent doxorubicin (DOX)-induced cardiotoxicity. BALB/c mice were …

Background Lack of a reliable hind limb gangrene animal model limits preclinical studies of
gangrene, a severe form of critical limb ischemia. We develop a novel mouse hind limb …

We report on the application of radon inhalation therapy to patients with 4 types of cancer:
colon, uterine, lung, and liver cell. The radon treatments were given to improve the efficacy …