Recent advances in neuropeptide signaling in Drosophila, from genes to physiology and behavior

DR Nässel, M Zandawala - Progress in neurobiology, 2019 - Elsevier
This review focuses on neuropeptides and peptide hormones, the largest and most diverse
class of neuroactive substances, known in Drosophila and other animals to play roles in …

Neuropeptides as regulators of behavior in insects

L Schoofs, A De Loof… - Annual Review of …, 2017 - annualreviews.org
Neuropeptides are by far the largest and most diverse group of signaling molecules in
multicellular organisms. They are ancient molecules important in regulating a multitude of …

[BOOK][B] Insect physiology and biochemistry

JL Nation Sr - 2022 - taylorfrancis.com
Employing the clear, student-friendly style that made previous editions so popular, Insect
Physiology and Biochemistry, Fourth Edition presents an engaging and authoritative guide …

A gene-specific T2A-GAL4 library for Drosophila

PT Lee, J Zirin, O Kanca, WW Lin, KL Schulze… - elife, 2018 - elifesciences.org
We generated a library of~ 1000 Drosophila stocks in which we inserted a construct in the
intron of genes allowing expression of GAL4 under control of endogenous promoters while …

Synaptic connectome of the Drosophila circadian clock

N Reinhard, A Fukuda, G Manoli, E Derksen… - Nature …, 2024 - nature.com
The circadian clock and its output pathways play a pivotal role in optimizing daily processes.
To obtain insights into how diverse rhythmic physiology and behaviors are orchestrated, we …

Hormonal axes in Drosophila: regulation of hormone release and multiplicity of actions

DR Nässel, M Zandawala - Cell and tissue research, 2020 - Springer
Hormones regulate development, as well as many vital processes in the daily life of an
animal. Many of these hormones are peptides that act at a higher hierarchical level in the …

A neuronal ensemble encoding adaptive choice during sensory conflict in Drosophila

PF Sareen, LY McCurdy, MN Nitabach - Nature communications, 2021 - nature.com
Feeding decisions are fundamental to survival, and decision making is often disrupted in
disease. Here, we show that neural activity in a small population of neurons projecting to the …

Substrates for Neuronal Cotransmission With Neuropeptides and Small Molecule Neurotransmitters in Drosophila

DR Nässel - Frontiers in cellular neuroscience, 2018 - frontiersin.org
It has been known for more than 40 years that individual neurons can produce more than
one neurotransmitter and that neuropeptides often are colocalized with small molecule …

A nutrient-responsive hormonal circuit mediates an inter-tissue program regulating metabolic homeostasis in adult Drosophila

T Koyama, S Terhzaz, MT Naseem, S Nagy… - Nature …, 2021 - nature.com
Animals maintain metabolic homeostasis by modulating the activity of specialized organs
that adjust internal metabolism to external conditions. However, the hormonal signals …

A peptidergic circuit links the circadian clock to locomotor activity

AN King, AF Barber, AE Smith, AP Dreyer, D Sitaraman… - Current Biology, 2017 - cell.com
The mechanisms by which clock neurons in the Drosophila brain confer an∼ 24-hr rhythm
onto locomotor activity are unclear, but involve the neuropeptide diuretic hormone 44 …