The reactivation of a stored memory in the brain can make the memory transiently labile.
During the time it takes for the memory to restabilize (reconsolidate) the memory can either …

Science fiction notions of altering problematic memories are starting to become reality as
techniques emerge through which unique memories can be edited. Here we review memory …

Research in nonhuman animals suggests that reactivation can induce a transient, unstable
state in a previously consolidated memory, during which the memory can be disrupted or …

Detecting novelty is critical to consolidate declarative memories, such as spatial contextual
recognition memory. It has been shown that stored memories, when retrieved, are …

Maladaptive reward memories (MRMs) are involved in the development and maintenance of
acquired overconsumption disorders, such as harmful alcohol and drug use. The process of …

Pioneering research over the past two decades has shown that memories are far more
malleable than we once thought, thereby highlighting the potential for new clinical avenues …

Since its rediscovery at the beginning of the 21st Century, memory reconsolidation has been
proposed to be a therapeutic target for reducing the impact of emotional memories that can …

Since the introduction of intravenous drug self-administration methodology over 50 years
ago, experimental investigation of addictive behaviour has delivered an enormous body of …

Background Consolidated memories can undergo enduring modification through retrieval-
dependent treatments that modulate reconsolidation. This represents a potentially …

Memory persistence is a double edge sword. Persistence of adaptive memories is essential
for survival and even determines who we are. Neurodegenerative conditions with significant …