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Coumarins as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies
Coumarins are fused benzene and pyrone ring systems which prompt biological
investigation to assess their potential therapeutic significance. It possesses immeasurable …
investigation to assess their potential therapeutic significance. It possesses immeasurable …
Recent developments of C-4 substituted coumarin derivatives as anticancer agents
Cancer is a prominent cause of death in global. Currently, the numbers of drugs that are in
clinical practice are having a high prevalence of side effect and multidrug resistance …
clinical practice are having a high prevalence of side effect and multidrug resistance …
Pechmann reaction in the synthesis of coumarin derivatives
The Pechmann reaction introduces one of the most significant and simple methods for the
synthesis of a variety of heterocyclic compounds, particularly coumarin derivatives. In 1883 …
synthesis of a variety of heterocyclic compounds, particularly coumarin derivatives. In 1883 …
Mechanochemical synthesis of coumarins via Pechmann condensation under solvent-free conditions: An easy access to coumarins and annulated pyrano [2, 3-f] and …
AD Sharapov, RF Fatykhov, IA Khalymbadzha… - Green …, 2022 - pubs.rsc.org
A green protocol has been developed for the synthesis of simple coumarins and linear
pyrano [2, 3-f] and [3, 2-f] indoles by the reaction of phenol derivatives with β-ketoesters …
pyrano [2, 3-f] and [3, 2-f] indoles by the reaction of phenol derivatives with β-ketoesters …
Heterogeneously Catalyzed Pechmann Condensation Employing the Tailored Zn0.925Ti0.075O NPs: Synthesis of Coumarin
A novel heterogeneous catalytic method was developed for the synthesis of coumarin and
its derivatives using the Ti (IV)-doped ZnO matrix forming catalyst Zn0. 925Ti0. 075O having …
its derivatives using the Ti (IV)-doped ZnO matrix forming catalyst Zn0. 925Ti0. 075O having …
Recent advances in the synthesis of coumarin derivatives via Pechmann condensation
The Pechmann condensation is the formation of coumarin derivatives from phenols and a
carboxylic acids or esters containing a β-carbonyl group under acidic conditions. The …
carboxylic acids or esters containing a β-carbonyl group under acidic conditions. The …
[HTML][HTML] FeCl3-catalysed ultrasonic-assisted, solvent-free synthesis of 4-substituted coumarins. A useful complement to the Pechmann reaction
The catalytic activity of FeCl 3 for the synthesis of a variety of 4-substituted coumarins using
high energy techniques has been investigated. The ultrasonic-assisted conditions provide a …
high energy techniques has been investigated. The ultrasonic-assisted conditions provide a …
Pentafluorophenylammonium triflate as an efficient, environmentally friendly and novel organocatalyst for synthesis of bis-indolyl methane derivatives
S Khaksar, SM Ostad - Journal of Fluorine Chemistry, 2011 - Elsevier
A simple, inexpensive, environmentally friendly and efficient route for the synthesis of bis-
indolyl methane derivatives by the reaction of indole or N-methyl indole with aldehydes …
indolyl methane derivatives by the reaction of indole or N-methyl indole with aldehydes …
Establishing a flow process to Coumarin‐8‐carbaldehydes as important synthetic scaffolds
Despite their usefulness as fluorophores and synthetic precursors, efficient and reliable
routes to coumarin‐8‐carbaldehydes are lacking. We describe here a high‐yielding …
routes to coumarin‐8‐carbaldehydes are lacking. We describe here a high‐yielding …
Synthesis and biological properties of coumarin analogue: A brief Review
D Chaudhary, P Bedi, S Santra… - Letters in Organic …, 2022 - benthamdirect.com
One of the most prominent aromatic organic chemical compound is Coumarin having
formula C9H6O2 which is widely known for its benefits in drug industry. Colourless …
formula C9H6O2 which is widely known for its benefits in drug industry. Colourless …