Antimicrobial resistance in ESKAPE pathogens

DMP De Oliveira, BM Forde, TJ Kidd… - Clinical microbiology …, 2020‏ - journals.asm.org
Antimicrobial-resistant ESKAPE (E nterococcus faecium, S taphylococcus aureus, K
lebsiella pneumoniae, A cinetobacter baumannii, P seudomonas aeruginosa, and E …

The impact of insertion sequences on bacterial genome plasticity and adaptability

J Vandecraen, M Chandler, A Aertsen… - Critical reviews in …, 2017‏ - Taylor & Francis
Transposable elements (TE), small mobile genetic elements unable to exist independently
of the host genome, were initially believed to be exclusively deleterious genomic parasites …

[HTML][HTML] The emergence of antibiotic resistance by mutation

N Woodford, MJ Ellington - Clinical Microbiology and Infection, 2007‏ - Elsevier
The emergence of mutations in nucleic acids is one of the major factors underlying
evolution, providing the working material for natural selection. Most bacteria are haploid for …

Modes and modulations of antibiotic resistance gene expression

F Depardieu, I Podglajen, R Leclercq… - Clinical microbiology …, 2007‏ - journals.asm.org
Since antibiotic resistance usually affords a gain of function, there is an associated
biological cost resulting in a loss of fitness of the bacterial host. Considering that antibiotic …

[HTML][HTML] Molecular Basis of Non-β-Lactam Antibiotics Resistance in Staphylococcus aureus

H Lade, HS Joo, JS Kim - Antibiotics, 2022‏ - mdpi.com
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most successful human
pathogens with the potential to cause significant morbidity and mortality. MRSA has …

The Quorum Sensing Inhibitor Hamamelitannin Increases Antibiotic Susceptibility of Staphylococcus aureus Biofilms by Affecting Peptidoglycan Biosynthesis and …

G Brackman, K Breyne, R De Rycke, A Vermote… - Scientific reports, 2016‏ - nature.com
Abstract Treatment of Staphylococcus aureus infections has become increasingly
challenging due to the rapid emergence and dissemination of methicillin-resistant strains. In …

Vancomycin resistance among methicillin resistant Staphylococcus aureus isolates from intensive care units of tertiary care hospitals in Hyderabad

V Thati, CT Shivannavar… - Indian Journal of Medical …, 2011‏ - journals.lww.com
Methods: MRSA were isolated and identified from different clinical samples collected from
ICUs of tertiary care hospitals in Hyderabad using conventional methods. Antibiogram of the …

Molecular Events for Promotion of Vancomycin Resistance in Vancomycin Intermediate Staphylococcus aureus

Q Hu, H Peng, X Rao - Frontiers in microbiology, 2016‏ - frontiersin.org
Vancomycin has been used as the last resort in the clinical treatment of serious
Staphylococcus aureus infections. Vancomycin-intermediate S. aureus (VISA) was …

Nosocomial infections by Staphylococcus epidermidis: how a commensal bacterium turns into a pathogen

W Ziebuhr, S Hennig, M Eckart, H Kränzler… - International journal of …, 2006‏ - Elsevier
Staphylococcus epidermidis is a commensal bacterium of the human skin. However, S.
epidermidis and other coagulase-negative staphylococci (CNS) emerge also as common …

Novel Mechanism of Antibiotic Resistance Originating in Vancomycin-Intermediate Staphylococcus aureus

L Cui, A Iwamoto, JQ Lian, H Neoh… - Antimicrobial agents …, 2006‏ - journals.asm.org
As an aggressive pathogen, Staphylococcus aureus poses a significant public health threat
and is becoming increasingly resistant to currently available antibiotics, including …