Antimicrobial peptides: A new hope in biomedical and pharmaceutical fields

A Moretta, C Scieuzo, AM Petrone, R Salvia… - Frontiers in cellular …, 2021 - frontiersin.org
Antibiotics are essential drugs used to treat pathogenic bacteria, but their prolonged use
contributes to the development and spread of drug-resistant microorganisms. Antibiotic …

Role of metabolic endotoxemia in systemic inflammation and potential interventions

S Mohammad, C Thiemermann - Frontiers in immunology, 2021 - frontiersin.org
Diet-induced metabolic endotoxemia is an important factor in the development of many
chronic diseases in animals and man. The gut epithelium is an efficient barrier that prevents …

Biofilms as promoters of bacterial antibiotic resistance and tolerance

C Uruén, G Chopo-Escuin, J Tommassen… - Antibiotics, 2020 - mdpi.com
Multidrug resistant bacteria are a global threat for human and animal health. However, they
are only part of the problem of antibiotic failure. Another bacterial strategy that contributes to …

A new era of antibiotics: the clinical potential of antimicrobial peptides

K Browne, S Chakraborty, R Chen… - International journal of …, 2020 - mdpi.com
Antimicrobial resistance is a multifaceted crisis, imposing a serious threat to global health.
The traditional antibiotic pipeline has been exhausted, prompting research into alternate …

Antibiotic‐free antibacterial strategies enabled by nanomaterials: progress and perspectives

Y Wang, Y Yang, Y Shi, H Song, C Yu - Advanced Materials, 2020 - Wiley Online Library
Bacterial infection is one of the top ten leading causes of death globally and the worst killer
in low‐income countries. The overuse of antibiotics leads to ever‐increasing antibiotic …

The dynamics of the skin's immune system

AV Nguyen, AM Soulika - International journal of molecular sciences, 2019 - mdpi.com
The skin is a complex organ that has devised numerous strategies, such as physical,
chemical, and microbiological barriers, to protect the host from external insults. In addition …

Nano-strategies to fight multidrug resistant bacteria—“A Battle of the Titans”

PV Baptista, MP McCusker, A Carvalho… - Frontiers in …, 2018 - frontiersin.org
Infectious diseases remain one of the leading causes of morbidity and mortality worldwide.
The WHO and CDC have expressed serious concern regarding the continued increase in …

Mode-of-action of antimicrobial peptides: membrane disruption vs. intracellular mechanisms

AH Benfield, ST Henriques - Frontiers in Medical Technology, 2020 - frontiersin.org
Antimicrobial peptides are an attractive alternative to traditional antibiotics, due to their
physicochemical properties, activity toward a broad spectrum of bacteria, and mode-of …

The role of IL-22 in intestinal health and disease

ME Keir, T Yi, TT Lu, N Ghilardi - Journal of Experimental Medicine, 2020 - rupress.org
The role of IL-22 in intestinal health and disease | Journal of Experimental Medicine |
Rockefeller University Press Skip to Main Content Advertisement Umbrella Alt Text …

Advances of peptides for antibacterial applications

Y Yan, Y Li, Z Zhang, X Wang, Y Niu, S Zhang… - Colloids and Surfaces B …, 2021 - Elsevier
In the past few decades, peptide antibacterial products with unique antibacterial
mechanisms have attracted widespread interest. They can effectively reduce the probability …