Polymeric micelles and cancer therapy: An ingenious multimodal tumor-targeted drug delivery system

SK Hari, A Gauba, N Shrivastava, RM Tripathi… - Drug Delivery and …, 2023 - Springer
Since the beginning of pharmaceutical research, drug delivery methods have been an
integral part of it. Polymeric micelles (PMs) have emerged as multifunctional nanoparticles in …

Polymeric micelles for the delivery of poorly soluble drugs: From nanoformulation to clinical approval

D Hwang, JD Ramsey, AV Kabanov - Advanced drug delivery reviews, 2020 - Elsevier
Over the last three decades, polymeric micelles have emerged as a highly promising drug
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …

Polyethylene glycol (PEG): a versatile polymer for pharmaceutical applications

AA D'souza, R Shegokar - Expert opinion on drug delivery, 2016 - Taylor & Francis
Introduction: Polyethylene glycol (PEG) is a polymer of choice in drug delivery systems. This
USFDA-approved polymer is popular due to its tunable properties and well-established …

Nanomicelles: Types, properties and applications in drug delivery

A Bose, D Roy Burman, B Sikdar… - IET …, 2021 - Wiley Online Library
Nanomicelles are self‐assembling nanosized (usually with particle size within a range of 10
to 100 nm) colloidal dispersions with a hydrophobic core and hydrophilic shell. Owing to its …

[HTML][HTML] Micelles structure development as a strategy to improve smart cancer therapy

NAN Hanafy, M El-Kemary, S Leporatti - Cancers, 2018 - mdpi.com
Micelles as colloidal suspension have attracted considerable attention due to their potential
use for both cancer diagnosis and therapy. These structures have proven their ability to …

Targeted drug delivery to tumors: myths, reality and possibility

YH Bae, K Park - Journal of controlled release, 2011 - Elsevier
The ultimate goal of drug delivery research is to help patients by develo** clinically useful
formulations. During the last several decades controlled drug delivery technology has …

Advances in polymeric micelles for drug delivery and tumor targeting

U Kedar, P Phutane, S Shidhaye, V Kadam - … Nanotechnology, Biology and …, 2010 - Elsevier
A plethora of formulation techniques have been reported in the literature for targeting drugs
to specific sites. Polymeric micelles (PMs) can be targeted to tumor sites by passive as well …

PEG–PLGA copolymers: Their structure and structure-influenced drug delivery applications

K Zhang, X Tang, J Zhang, W Lu, X Lin, Y Zhang… - Journal of Controlled …, 2014 - Elsevier
In the paper, we begin by describing polyethylene glycol–poly lactic acid-co-glycolic acid
(PEG–PLGA) which was chosen as a typical model copolymer for the construction of nano …

Applications of polymer micelles for imaging and drug delivery

S Movassaghian, OM Merkel… - Wiley Interdisciplinary …, 2015 - Wiley Online Library
Polymeric micelles, self‐assembling nano‐constructs of amphiphilic copolymers, are widely
considered as convenient nano‐carriers for a variety of applications, such as diagnostic …

Physical stimuli-responsive polymeric micelles for anti-cancer drug delivery

N Rapoport - Progress in Polymer Science, 2007 - Elsevier
Block copolymer micelles are generally formed by self-assembly of amphiphilic copolymer
molecules in an aqueous milieu. The hydrophobic blocks (or polyion complexes) form the …