Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …

Cytochrome c oxidase (CcO), the terminal oxidase of cell respiration, reduces molecular
oxygen (O2) in a reaction that is coupled with proton pum**. Since the discovery of this …

Heme-copper oxidases (HCOs) are terminal enzymes on the mitochondrial or bacterial
respiratory electron transport chain, which utilize a unique heterobinuclear active site to …

Transition metal-driven small molecule activation is essential for the production of fuels and
chemicals or energy supply. The use of multimetallic catalysts, where two or more metal …

The majority of modern organisms, including many prokaryotes, are aerobes; 1 that is, they
use molecular oxygen as the terminal electron acceptor for energy generation. Although …

We studied the selectivity of a functional model of cytochrome c oxidase's active site that
mimics the coordination environment and relative locations of Fea3, CuB, and Tyr244. To …

Cytochrome c oxidases, or more generally hemecopper oxidases (see section 2), have for a
considerable time attracted the interest of modeling chemists. This is due to the importance …

With increasing demand for clean energy and approaching commercialization of polymer
electrolyte membrane fuel cells (PEMFCs), replacing expensive Pt-based cathode catalysts …

Lead has been used as a heavy atom derivative to solve the phase problem in the crystal
structures of a variety of protein including the calcium proteins calmodulin and …

The development of bioinspired catalysts for oxygen reduction reaction is one of the most
prominent pathways in the search for active materials to replace Pt-based catalysts in fuel …