Interaction of metal complexes with G‐quadruplex DNA
Guanine‐rich sequences of DNA can assemble into tetrastranded structures known as G‐
quadruplexes. It has been suggested that these secondary DNA structures could be …
quadruplexes. It has been suggested that these secondary DNA structures could be …
Four-stranded nucleic acids: structure, function and targeting of G-quadruplexes
JL Huppert - Chemical Society Reviews, 2008 - pubs.rsc.org
There are many structures that can be adopted by nucleic acids other than the famous
Watson–Crick duplex form. This tutorial review describes the guanine rich G-quadruplex …
Watson–Crick duplex form. This tutorial review describes the guanine rich G-quadruplex …
Structure, location and interactions of G‐quadruplexes
JL Huppert - The FEBS journal, 2010 - Wiley Online Library
Four‐stranded G‐rich DNA structures called G‐quadruplexes have been the subject of
increasing interest recently. Experimental and computational techniques have been used to …
increasing interest recently. Experimental and computational techniques have been used to …
Chemical-biology approaches to probe DNA and RNA G-quadruplex structures in the genome
G-quadruplexes are nucleic acids secondary structures that can be formed in guanine-rich
sequences. More than 30 years ago, their formation was first observed in telomeric DNA …
sequences. More than 30 years ago, their formation was first observed in telomeric DNA …
Hunting G-quadruplexes
JL Huppert - Biochimie, 2008 - Elsevier
Whilst DNA spends much of its time in the double-stranded form, frequently in storage,
wrapped around histones and packaged as chromatin, it can also form other complex …
wrapped around histones and packaged as chromatin, it can also form other complex …
Co-transcriptional formation of DNA:RNA hybrid G-quadruplex and potential function as constitutional cis element for transcription control
G-quadruplex formation in genomic DNA is considered to regulate transcription. Previous
investigations almost exclusively focused on intramolecular G-quadruplexes formed by DNA …
investigations almost exclusively focused on intramolecular G-quadruplexes formed by DNA …
[HTML][HTML] TMPyP4 promotes cancer cell migration at low doses, but induces cell death at high doses
XH Zheng, X Nie, HY Liu, YM Fang, Y Zhao, LX **a - Scientific reports, 2016 - nature.com
TMPyP4 is widely considered as a potential photosensitizer in photodynamic therapy and a
G-quadruplex stabilizer for telomerase-based cancer therapeutics. However, its biological …
G-quadruplex stabilizer for telomerase-based cancer therapeutics. However, its biological …
Tridentate N‐Donor Palladium (II) Complexes as Efficient Coordinating Quadruplex DNA Binders
Fifteen complexes of palladium, platinum, and copper, featuring five different N‐donor
tridentate (terpyridine‐like) ligands, were prepared with the aim of testing their G …
tridentate (terpyridine‐like) ligands, were prepared with the aim of testing their G …
Nucleic acid-metal ion interactions
NV Hud - 2009 - books.google.com
Natural biochemical processes are routinely being discovered in living cells that involve
RNA. Some of these processes, such as RNA interference, are now being exploited for …
RNA. Some of these processes, such as RNA interference, are now being exploited for …
Molecular mechanisms of congenital heart disease
H **g-bin, L Ying-long, S Pei-wu, L **ao-dong… - Cardiovascular …, 2010 - Elsevier
BACKGROUND: Congenital heart disease (CHD) is the most common type of birth defect.
Despite the many advances in our understanding of cardiac development and many genes …
Despite the many advances in our understanding of cardiac development and many genes …