Over Six Thousand Trypanosoma cruzi Strains Classified into Discrete Ty** Units (DTUs): Attempt at an Inventory

SF Brenière, E Waleckx, C Barnabé - PLoS neglected tropical …, 2016 - journals.plos.org
Trypanosoma cruzi, the causative agent of Chagas disease, presents wide genetic diversity.
Currently, six discrete ty** units (DTUs), named TcI to TcVI, and a seventh one called …

Animal models for exploring Chagas disease pathogenesis and supporting drug discovery

AA Khan, MC Taylor, A Fortes Francisco… - Clinical microbiology …, 2024 - journals.asm.org
Infections with the parasitic protozoan Trypanosoma cruzi cause Chagas disease, which
results in serious cardiac and/or digestive pathology in 30%–40% of individuals. However …

Detailed ecological associations of triatomines revealed by metabarcoding and next-generation sequencing: implications for triatomine behavior and Trypanosoma …

E Dumonteil, MJ Ramirez-Sierra, S Pérez-Carrillo… - Scientific reports, 2018 - nature.com
Trypanosoma cruzi is the agent of Chagas disease, transmitted by hematophagous
triatomine vectors. Establishing transmission cycles is key to understand the epidemiology of …

The economic value of identifying and treating Chagas disease patients earlier and the impact on Trypanosoma cruzi transmission

SM Bartsch, CM Avelis, L Asti… - PLoS neglected …, 2018 - journals.plos.org
Background The World Health Organization's 2020 Goals for Chagas disease include
access to antiparasitic treatment and care of all infected/ill patients. Policy makers need to …

[HTML][HTML] Deep sequencing reveals multiclonality and new discrete ty** units of Trypanosoma cruzi in rodents from the southern United States

H Pronovost, AC Peterson, BG Chavez, MJ Blum… - Journal of Microbiology …, 2020 - Elsevier
Background/purpose The parasitic protozoa Trypanosoma cruzi, is widely distributed
throughout the Americas. We explored the nature of T. cruzi infection in small rodents from …

Molecular identification and genoty** of Trypanosoma cruzi DNA in autochthonous Chagas disease patients from Texas, USA

MN Garcia, H Burroughs, R Gorchakov… - Infection, genetics and …, 2017 - Elsevier
The parasitic protozoan Trypanosoma cruzi, the causative agent of Chagas disease, is
widely distributed throughout the Americas, from the southern United States (US) to northern …

Uncovering vector, parasite, blood meal and microbiome patterns from mixed-DNA specimens of the Chagas disease vector Triatoma dimidiata

LC Orantes, C Monroy, PL Dorn… - PLoS neglected …, 2018 - journals.plos.org
Chagas disease, considered a neglected disease by the World Health Organization, is
caused by the protozoan parasite Trypanosoma cruzi, and transmitted by> 140 triatomine …

The diversity of the Chagas parasite, Trypanosoma cruzi, infecting the main Central American vector, Triatoma dimidiata, from Mexico to Colombia

PL Dorn, AG McClure, MD Gallaspy… - PloS neglected …, 2017 - journals.plos.org
Little is known about the strains of Trypanosoma cruzi circulating in Central America and
specifically in the most important vector in this region, Triatoma dimidiata. Approximately six …

Cancer risk landscapes: A framework to study cancer in ecosystems

AM Dujon, B Ujvari, F Thomas - Science of the Total Environment, 2021 - Elsevier
Cancer is a family of diseases that has been documented in most metazoan species and
ecosystems. Human induced environmental changes are increasingly exposing wildlife to …

Geographical, landscape and host associations of Trypanosoma cruzi DTUs and lineages

A Izeta-Alberdi, CN Ibarra-Cerdeña, DA Moo-Llanes… - Parasites & …, 2016 - Springer
Background The evolutionary history and ecological associations of Trypanosoma cruzi, the
need to identify genetic markers that can distinguish parasite subpopulations, and …