Antiseizure medications for adults with epilepsy: a review

AM Kanner, MM Bicchi - Jama, 2022 - jamanetwork.com
Importance Epilepsy affects approximately 65 million people worldwide. Persistent seizures
are associated with a 20% to 40% risk of bodily injuries (eg, fractures, burns, concussions) …

Adult epilepsy

AA Asadi-Pooya, F Brigo, S Lattanzi, I Blumcke - The Lancet, 2023 - thelancet.com
Epilepsy is a common medical condition that affects people of all ages, races, social classes,
and geographical regions. Diagnosis of epilepsy remains clinical, and ancillary …

International League Against Epilepsy classification and definition of epilepsy syndromes with onset in childhood: Position paper by the ILAE Task Force on Nosology …

N Specchio, EC Wirrell, IE Scheffer, R Nabbout… - …, 2022 - Wiley Online Library
Abstract The 2017 International League Against Epilepsy classification has defined a three‐
tier system with epilepsy syndrome identification at the third level. Although a syndrome …

A prognostic neural epigenetic signature in high-grade glioma

R Drexler, R Khatri, T Sauvigny, M Mohme, CL Maire… - Nature Medicine, 2024 - nature.com
Neural–tumor interactions drive glioma growth as evidenced in preclinical models, but
clinical validation is limited. We present an epigenetically defined neural signature of …

ILAE classification and definition of epilepsy syndromes with onset in neonates and infants: Position statement by the ILAE Task Force on Nosology and Definitions

SM Zuberi, E Wirrell, E Yozawitz, JM Wilmshurst… - …, 2022 - Wiley Online Library
Abstract The International League Against Epilepsy (ILAE) Task Force on Nosology and
Definitions proposes a classification and definition of epilepsy syndromes in the neonate …

ILAE definition of the idiopathic generalized epilepsy syndromes: position statement by the ILAE task force on nosology and definitions

E Hirsch, J French, IE Scheffer, A Bogacz, T Alsaadi… - …, 2022 - Wiley Online Library
Abstract In 2017, the International League Against Epilepsy (ILAE) Classification of
Epilepsies described the “genetic generalized epilepsies”(GGEs), which contained the …

Interleukin 6: at the interface of human health and disease

E Grebenciucova, S VanHaerents - Frontiers in immunology, 2023 - frontiersin.org
Interleukin 6 (IL-6) is a pleiotropic cytokine executing a diverse number of functions, ranging
from its effects on acute phase reactant pathways, B and T lymphocytes, blood brain barrier …

The epidemiology of epilepsy

E Beghi - Neuroepidemiology, 2020 - karger.com
Epilepsy is a chronic disease of the brain characterized by an enduring (ie, persisting)
predisposition to generate seizures, unprovoked by any immediate central nervous system …

Methodology for classification and definition of epilepsy syndromes with list of syndromes: report of the ILAE Task Force on Nosology and Definitions

EC Wirrell, R Nabbout, IE Scheffer, T Alsaadi… - …, 2022 - Wiley Online Library
Epilepsy syndromes have been recognized for> 50 years, as distinct electroclinical
phenotypes with therapeutic and prognostic implications. Nonetheless, no formally accepted …

The pharmacology and clinical efficacy of antiseizure medications: from bromide salts to cenobamate and beyond

W Löscher, P Klein - CNS drugs, 2021 - Springer
Epilepsy is one of the most common and disabling chronic neurological disorders.
Antiseizure medications (ASMs), previously referred to as anticonvulsant or antiepileptic …