[HTML][HTML] Bilayer forming phospholipids as targets for cancer therapy

C Stoica, AK Ferreira, K Hannan, M Bakovic - International journal of …, 2022 - mdpi.com
Phospholipids represent a crucial component for the structure of cell membranes.
Phosphatidylcholine and phosphatidylethanolamine are two phospholipids that comprise …

[HTML][HTML] Lipid profile in breast cancer: From signaling pathways to treatment strategies

HT Ribas, MC Sogayar, AM Dolga, SMB Winnischofer… - Biochimie, 2024 - Elsevier
Breast cancer is the most prevalent cancer in women. Metabolic abnormalities, particularly
increased lipid synthesis and uptake, impact the onset and progression of the disease …

Gut Microbiota Mediates Lactobacillus rhamnosus GG Alleviation of Deoxynivalenol-Induced Anorexia

Y Bai, Q Meng, C Wang, K Ma, J Li, J Li… - Journal of Agricultural …, 2023 - ACS Publications
Deoxynivalenol (DON) is a widespread mycotoxin and causes anorexia and emesis in
humans and animals; Lactobacillus rhamnosus GG (LGG), a well-characterized probiotic …

Toxic effects of fragmented polyethylene terephthalate particles on the marine rotifer Brachionus koreanus: Based on ingestion and egestion assay, in vivo toxicity test …

JW Yoo, JS Park, YH Lee, TJ Choi, CB Kim… - Journal of Hazardous …, 2024 - Elsevier
Microplastics (MPs) are a major concern in marine ecosystem because MPs are persistent
and ubiquitous in oceans and are easily consumed by marine biota. Although many studies …

Lipidome profile predictive of disease evolution and activity in rheumatoid arthritis

JH Koh, SJ Yoon, M Kim, S Cho, J Lim, Y Park… - … & molecular medicine, 2022 - nature.com
Lipid mediators are crucial for the pathogenesis of rheumatoid arthritis (RA); however, global
analyses have not been undertaken to systematically define the lipidome underlying the …

Functional metabolomics reveals arsenic-induced inhibition of linoleic acid metabolism in mice kidney in drinking water

T He, L **ong, K Lin, J Yi, C Duan, J Zhang - Environmental Pollution, 2024 - Elsevier
Arsenic (As) is a heavy metal known for its detrimental effects on the kidneys, but the precise
mechanisms underlying its toxicity remain unclear. In this study, we employed an integrated …

[HTML][HTML] Choosing the right animal model for renal cancer research

P Sobczuk, A Brodziak, MI Khan, S Chhabra… - Translational …, 2020 - Elsevier
The increase in the life expectancy of patients with renal cell carcinoma (RCC) in the last
decade is due to changes that have occurred in the area of preclinical studies …

[HTML][HTML] Context-dependent roles for ubiquitous mitochondrial creatine kinase CKMT1 in breast cancer progression

V Ayyappan, NM Jenkinson, CM Tressler, Z Tan… - Cell reports, 2024 - cell.com
Metabolic reprogramming is a hallmark of cancer, enabling cancer cells to rapidly
proliferate, invade, and metastasize. We show that creatine levels in metastatic breast …

Lipid alterations in glioma: a systematic review

K Abdul Rashid, K Ibrahim, JHD Wong, N Mohd Ramli - Metabolites, 2022 - mdpi.com
Gliomas are highly lethal tumours characterised by heterogeneous molecular features,
producing various metabolic phenotypes leading to therapeutic resistance. Lipid metabolism …

[HTML][HTML] Discovering metabolic vulnerability using spatially resolved metabolomics for antitumor small molecule-drug conjugates development as a precise cancer …

X Wang, J Zhang, K Zheng, Q Du, G Wang… - Journal of …, 2023 - Elsevier
Against tumor-dependent metabolic vulnerability is an attractive strategy for tumor-targeted
therapy. However, metabolic inhibitors are limited by the drug resistance of cancerous cells …