Coupling mechanism and significance of the BOLD signal: a status report

EMC Hillman - Annual review of neuroscience, 2014 - annualreviews.org
Functional magnetic resonance imaging (fMRI) provides a unique view of the working
human mind. The blood-oxygen-level-dependent (BOLD) signal, detected in fMRI, reflects …

[HTML][HTML] Time to wake up: Studying neurovascular coupling and brain-wide circuit function in the un-anesthetized animal

YR Gao, Y Ma, Q Zhang, AT Winder, Z Liang, L Antinori… - Neuroimage, 2017 - Elsevier
Functional magnetic resonance imaging (fMRI) has allowed the noninvasive study of task-
based and resting-state brain dynamics in humans by inferring neural activity from blood …

Resting-state hemodynamics are spatiotemporally coupled to synchronized and symmetric neural activity in excitatory neurons

Y Ma, MA Shaik, MG Kozberg, SH Kim… - Proceedings of the …, 2016 - pnas.org
Brain hemodynamics serve as a proxy for neural activity in a range of noninvasive
neuroimaging techniques including functional magnetic resonance imaging (fMRI). In …

Dynamic modulation of decision biases by brainstem arousal systems

JW de Gee, O Colizoli, NA Kloosterman, T Knapen… - elife, 2017 - elifesciences.org
Decision-makers often arrive at different choices when faced with repeated presentations of
the same evidence. Variability of behavior is commonly attributed to noise in the brain's …

Compressive spatial summation in human visual cortex

KN Kay, J Winawer, A Mezer… - Journal of …, 2013 - journals.physiology.org
Neurons within a small (a few cubic millimeters) region of visual cortex respond to stimuli
within a restricted region of the visual field. Previous studies have characterized the …

Large-scale imaging of cortical dynamics during sensory perception and behavior

JB Wekselblatt, ED Flister… - Journal of …, 2016 - journals.physiology.org
Sensory-driven behaviors engage a cascade of cortical regions to process sensory input
and generate motor output. To investigate the temporal dynamics of neural activity at this …

High-speed volumetric two-photon fluorescence imaging of neurovascular dynamics

JL Fan, JA Rivera, W Sun, J Peterson… - Nature …, 2020 - nature.com
Understanding the structure and function of vasculature in the brain requires us to monitor
distributed hemodynamics at high spatial and temporal resolution in three-dimensional (3D) …

Weak correlations between hemodynamic signals and ongoing neural activity during the resting state

AT Winder, C Echagarruga, Q Zhang, PJ Drew - Nature neuroscience, 2017 - nature.com
Spontaneous fluctuations in hemodynamic signals in the absence of a task or overt
stimulation are used to infer neural activity. We tested this coupling by simultaneously …

Aging drives cerebrovascular network remodeling and functional changes in the mouse brain

HC Bennett, Q Zhang, Y Wu, SB Manjila… - Nature …, 2024 - nature.com
Aging is frequently associated with compromised cerebrovasculature and pericytes.
However, we do not know how normal aging differentially impacts vascular structure and …

The brain's default network: origins and implications for the study of psychosis

RL Buckner - Dialogues in clinical neuroscience, 2013 - Taylor & Francis
The brain's default network is a set of regions that is spontaneously active during passive
moments. The network is also active during directed tasks that require participants to …