In the past decade, leptospirosis has emerged as a globally important infectious disease. It
occurs in urban environments of industrialised and develo** countries, as well as in rural …

Leptospirosis, the most widespread zoonosis in the world, is an emerging public health
problem, particularly in large urban centers of develo** countries. Several pathogenic …

Bacterial lipoproteins are synthesized as precursors in the cytoplasm and processed into
mature forms on the cytoplasmic membrane. A lipid moiety attached to the N terminus …

Leptospira species colonize a significant proportion of rodent populations worldwide and
produce life-threatening infections in accidental hosts, including humans. Complete genome …

Proteins with bacterial immunoglobulin‐like (Big) domains, such as the Yersinia
pseudotuberculosis invasin and Escherichia coli intimin, are surface‐expressed proteins …

Escherichia coli lipoproteins are anchored to the periplasmic surface of the inner or outer
membrane depending on the sorting signal. An ATP-binding cassette (ABC) transporter …

Pathogenic spirochetes are the causative agents of several important diseases including
syphilis, Lyme disease, leptospirosis, swine dysentery, periodontal disease and some forms …

We report novel features of the genome sequence of Leptospira interrogans serovar
Copenhageni, a highly invasive spirochete. Leptospira species colonize a significant …

Recombinant leptospiral outer membrane proteins (OMPs) can elicit immunity to
leptospirosis in a hamster infection model. Previously characterized OMPs appear highly …

ABSTRACT The Lyme disease spirochete, Borrelia burgdorferi, causes persistent
mammalian infection despite the development of vigorous immune responses against the …