Clinical summary of fibroblast activation protein inhibitor-based radiopharmaceuticals: cancer and beyond

M Li, MH Younis, Y Zhang, W Cai, X Lan - European journal of nuclear …, 2022 - Springer
Fibroblast activation protein (FAP) is a type II membrane-bound glycoprotein which is
overexpressed in cancer-associated fibroblasts and activated fibroblasts at wound …

[HTML][HTML] FAPI-avid nonmalignant PET/CT findings: an expedited systematic review

M Bentestuen, N Al-Obaydi, HD Zacho - Seminars in Nuclear Medicine, 2023 - Elsevier
Fibroblast activation protein inhibitor (FAPI) is a promising tracer in oncologic positron
emission tomography/computed tomography (PET/CT). Numerous studies have …

Pitfalls and common findings in 68Ga-FAPI PET: a pictorial analysis

L Kessler, J Ferdinandus, N Hirmas… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Fibroblast activation protein inhibitor (FAPI) PET/CT is a new tool in the diagnostic workup of
cancer. With a growing volume of applications, pitfalls and common findings need to be …

Cardiac fibroblast activation in patients early after acute myocardial infarction: integration with MR tissue characterization and subsequent functional outcome

J Diekmann, T Koenig, JT Thackeray… - Journal of Nuclear …, 2022 - Soc Nuclear Med
After acute myocardial infarction (AMI), fibroblast activation protein (FAP) upregulation
exceeds the infarct region. We sought further insights into the physiologic relevance by …

Emerging molecular imaging targets and tools for myocardial fibrosis detection

AK Barton, E Tzolos, R Bing, T Singh… - European Heart …, 2023 - academic.oup.com
Myocardial fibrosis is the heart's common healing response to injury. While initially seeking
to optimize the strength of diseased tissue, fibrosis can become maladaptive, producing stiff …

Post-myocardial infarction fibrosis: Pathophysiology, examination, and intervention

X Yin, X Yin, X Pan, J Zhang, X Fan, J Li… - Frontiers in …, 2023 - frontiersin.org
Cardiac fibrosis plays an indispensable role in cardiac tissue homeostasis and repair after
myocardial infarction (MI). The cardiac fibroblast-to-myofibroblast differentiation and …

Fibroblast activation protein imaging in reperfused ST-elevation myocardial infarction: comparison with cardiac magnetic resonance imaging

B **e, J Wang, XY **, X Guo, BX Chen, L Li… - European Journal of …, 2022 - Springer
Purpose The aim of this study was to explore the correlation of 18 F-labeled fibroblast
activation protein inhibitor (FAPI) and cardiovascular magnetic resonance (CMR) …

[68Ga]Ga-DOTA-FAPI-04 PET/MR in patients with acute myocardial infarction: potential role of predicting left ventricular remodeling

M Zhang, W Quan, T Zhu, S Feng, X Huang… - European journal of …, 2023 - Springer
Purpose To assess predictive value of 68Ga-labeled fibroblast activation protein inhibitor-04
([68Ga] Ga-DOTA-FAPI-04) PET/MR for late left ventricular (LV) remodeling in patients with …

Myocardial fibrosis: emerging target for cardiac molecular imaging and opportunity for image-guided therapy

FM Bengel, J Diekmann, A Hess… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Myocardial fibrosis is a major contributor to the development and progression of heart
failure. Significant progress in the understanding of its pathobiology has led to the …

Multimodality advanced cardiovascular and molecular imaging for early detection and monitoring of cancer therapy-associated cardiotoxicity and the role of artificial …

JM Kwan, EK Oikonomou, ML Henry… - Frontiers in …, 2022 - frontiersin.org
Cancer mortality has improved due to earlier detection via screening, as well as due to novel
cancer therapies such as tyrosine kinase inhibitors and immune checkpoint inhibitions …