Significance: Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique to
distinguish the unique molecular environment of fluorophores. FLIM measures the time a …

Rare-earth (RE) doped nanoparticles show unique features of photon conversion from an
incident wavelength to a more suitable wavelength at an intended biological site, thus …

Fluorescence lifetime imaging (FLIM) is a key fluorescence microscopy technique to map the
environment and interaction of fluorescent probes. It can report on photophysical events that …

Protein–membrane interactions (PMIs) are ubiquitous in cellular signaling. Initial steps of
signal transduction cascades often rely on transient and dynamic interactions with the inner …

Photoluminescent gold nanoclusters have attracted an extensive research interest in
bioimaging and therapeutics due to several distinctive advantages such as high fluorescent …

Optical imaging is a most useful and widespread technique for the investigation of the
structure and function of the cellular genomes. However, an analysis of immensely …

Förster resonance energy transfer (FRET) is a powerful tool to investigate the interaction
between proteins in living cells. Fluorescence proteins, such as the green fluorescent …

Optical imaging assays, especially fluorescence molecular assays, are minimally invasive if
not completely noninvasive, and thus an ideal technique to be applied to live specimens …

The insensitivity of multiphoton microscopy to optical scattering enables high-resolution,
high-contrast imaging deep into tissue, including in live animals. Scattering does, however …

The transition dipole moment of organic dyes PM546 and rhodamine 123 is calculated from
fluorescence lifetime measurements in solutions of different refractive index. A model …