Comparative analysis estimates the relative frequencies of co-divergence and cross-species transmission within viral families

JL Geoghegan, S Duchêne, EC Holmes - PLoS pathogens, 2017 - journals.plos.org
The cross-species transmission of viruses from one host species to another is responsible
for the majority of emerging infections. However, it is unclear whether some virus families …

Mutation and recombination in pathogen evolution: Relevance, methods and controversies

M Arenas, NM Araujo, C Branco, N Castelhano… - Infection, Genetics and …, 2018 - Elsevier
Mutation and recombination drive the evolution of most pathogens by generating the genetic
variants upon which selection operates. Those variants can, for example, confer resistance …

Consequences of substitution model selection on protein ancestral sequence reconstruction

R Del Amparo, M Arenas - Molecular biology and evolution, 2022 - academic.oup.com
The selection of the best-fitting substitution model of molecular evolution is a traditional step
for phylogenetic inferences, including ancestral sequence reconstruction (ASR). However, a …

Bioinformatics applied to biotechnology: A review towards bioenergy research

LM De Carvalho, G Borelli, AP Camargo… - Biomass and …, 2019 - Elsevier
The ever-increasing demand for energy, along with worldwide policies aiming sustainability,
resulted in an escalation of research projects focusing on alternative routes for energy …

Discovery of novel crustacean and cephalopod flaviviruses: insights into the evolution and circulation of flaviviruses between marine invertebrate and vertebrate hosts

R Parry, S Asgari - Journal of Virology, 2019 - Am Soc Microbiol
Most described flaviviruses (family Flaviviridae) are disease-causing pathogens of
vertebrates maintained in zoonotic cycles between mosquitoes or ticks and vertebrate hosts …

Anchored phylogenomics unravels the evolution of spider flies (Diptera, Acroceridae) and reveals discordance between nucleotides and amino acids

JP Gillung, SL Winterton, KM Bayless, Z Khouri… - Molecular phylogenetics …, 2018 - Elsevier
The onset of phylogenomics has contributed to the resolution of numerous challenging
evolutionary questions while offering new perspectives regarding biodiversity. However, in …

Can sequence phylogenies safely infer the origin of the global virome?

EC Holmes, S Duchêne - MBio, 2019 - Am Soc Microbiol
Edward C. Holmes, a, b, c Sebastián Duchêned aMarie Bashir Institute for Infectious
Diseases and Biosecurity, The University of Sydney, Sydney, NSW, Australia bCharles …

Relative model fit does not predict topological accuracy in single-gene protein phylogenetics

SJ Spielman - Molecular biology and evolution, 2020 - academic.oup.com
It is regarded as best practice in phylogenetic reconstruction to perform relative model
selection to determine an appropriate evolutionary model for the data. This procedure ranks …

Impact of the tree prior on estimating clock rates during epidemic outbreaks

S Möller, L du Plessis, T Stadler - Proceedings of the …, 2018 - National Acad Sciences
Bayesian phylogenetics aims at estimating phylogenetic trees together with evolutionary
and population dynamic parameters based on genetic sequences. It has been noted that the …

New statistical criteria detect phylogenetic bias caused by compositional heterogeneity

DA Duchêne, S Duchêne… - Molecular Biology and …, 2017 - academic.oup.com
In statistical phylogenetic analyses of DNA sequences, models of evolutionary change
commonly assume that base composition is stationary through time and across lineages …