Nogo-A is one of several neurite growth inhibitory components present in oligodendrocytes
and CNS myelin membranes. Nogo has a crucial role in restricting axonal regeneration and …

Thirty years ago, patients with spinal cord injury (SCI) and their families were told “nothing
can be done” to improve function. Since the SCI patient population is reaching normal life …

Reaching and gras** in primates depend on the coordination of neural activity in large
frontoparietal ensembles. Here we demonstrate that primates can learn to reach and grasp …

Mimicking soft tissue mechanical properties and the high conductivity required for electrical
transmission in the native spinal cord is critical in nerve tissue regeneration scaffold designs …

Spinal cord injuries (SCIs) in humans, and experimental animals,,, are often associated with
varying degrees of spontaneous functional recovery during the first months after injury. Such …

In the central nervous system (CNS), the transcription factor nuclear factor (NF)-κ B is a key
regulator of inflammation and secondary injury processes. After trauma or disease, the …

The maturation of nanotechnology has revealed it to be a unique and distinct discipline
rather than a specialization within a larger field. Its textbook cannot afford to be a chemistry …

Spinal cord injury (SCI) represents a central nervous system disaster, resulting in the
destruction of spinal cord structure and function and the formation of an adverse …

Spinal cord injury (SCI) can cause permanent loss of sensory and motor function, and there
is no effective clinical treatment, to date. Due to the complex pathological process involved …

The transplantation of neural stem/progenitor cells (NPCs) is a promising therapeutic
strategy for spinal cord injury (SCI). However, to date NPC transplantation has exhibited only …