The effectiveness of probiotics in the treatment of inflammatory bowel disease (IBD)—a critical review

D Jakubczyk, K Leszczyńska, S Górska - Nutrients, 2020 - mdpi.com
Inflammatory bowel disease (IBD), which affects millions of people worldwide, includes two
separate diseases: Crohn's disease (CD) and ulcerative colitis (UC). Although the …

[HTML][HTML] The unregulated probiotic market

C De Simone - Clinical Gastroenterology and Hepatology, 2019 - Elsevier
Background & Aims This narrative review provides an overview of the current regulation of
probiotics, with a focus on those used for the dietary management of medical conditions …

The gut microbiota at the intersection of bile acids and intestinal carcinogenesis: an old story, yet mesmerizing

T Liu, X Song, S Khan, Y Li, Z Guo, C Li… - … journal of cancer, 2020 - Wiley Online Library
The prevalence of colorectal cancer (CRC) has markedly increased worldwide in the last
decade. Alterations of bile acid metabolism and gut microbiota have been reported to play …

Bile salt hydrolase-competent probiotics in the management of IBD: Unlocking the “bile acid code”

RM Gadaleta, M Cariello, L Crudele, A Moschetta - Nutrients, 2022 - mdpi.com
Bile acid (BA) species and the gut microbiota (GM) contribute to intestinal mucosa
homeostasis. BAs shape the GM and, conversely, intestinal bacteria with bile salt hydrolase …

[HTML][HTML] Applying probiotics and prebiotics in new delivery formats–is the clinical evidence transferable?

M Cunningham, G Vinderola… - Trends in Food Science …, 2021 - Elsevier
Background There is substantial demand for gut health products incorporating probiotics
and prebiotics. They are being delivered as ingredients in an increasing range of different …

[HTML][HTML] Anti-inflammatory and analgesic potential of leaf extract of Justicia adhatoda L.(Acanthaceae) in Carrageenan and Formalin-induced models by targeting …

A Basit, T Shutian, A Khan, SM Khan… - Biomedicine & …, 2022 - Elsevier
Plants are regarded as a valuable and inexpensive source of new drug development, and a
variety of plant compounds are now being used in clinical trials to treat a variety of ailments …

Probiotics in the next-generation sequencing era

J Suez, N Zmora, E Elinav - Gut microbes, 2020 - Taylor & Francis
Technological developments, including massively parallel DNA sequencing, gnotobiotics,
metabolomics, RNA sequencing and culturomics, have markedly propelled the field of …

Ameliorative effect of surface proteins of probiotic lactobacilli in colitis mouse models

PR Chandhni, D Pradhan, K Sowmya, S Gupta… - Frontiers in …, 2021 - frontiersin.org
The increase in concern from viable cells of probiotics specifically in acute inflammatory
conditions has led to the emergence of the concept of postbiotics as a safer alternative …

Self-nanoemulsifying drug delivery system of genkwanin: a novel approach for anti-colitis-associated colorectal cancer

HF Yin, CM Yin, T Ouyang, SD Sun… - Drug Design …, 2021 - Taylor & Francis
Purpose The aim of the present study was to develop an optimized Genkwanin (GKA)-
loaded self-nanoemulsifying drug delivery system (SNEDDS) formulation to enhance the …

Self-nanoemulsifying drug delivery system of bruceine D: a new approach for anti-ulcerative colitis

YX Dou, JT Zhou, TT Wang, YF Huang… - International journal …, 2018 - Taylor & Francis
Background Bruceine D (BD) is a major bioactive component isolated from the traditional
Chinese medicinal plant Brucea javanica which has been widely utilized to treat dysentery …