As antibiotic-resistant bacteria and genes continue to emerge, the identification of effective
alternatives to traditional antibiotics has become a pressing issue. Antimicrobial peptides …

Highlights•Artificial intelligence (AI) is transforming the drug discovery process by providing
actionable insights from huge amount of data.•Deep-learning models, especially generative …

With their diverse biological activities, peptides are promising candidates for therapeutic
applications, showing antimicrobial, antitumour and hormonal signalling capabilities …

Peptides can bind challenging disease targets with high affinity and specificity, offering
enormous opportunities for addressing unmet medical needs. However, peptides' unique …

The process of design/discovery of drugs involves the identification and design of novel
molecules that have the desired properties and bind well to a given disease-relevant target …

Bioactive peptide therapeutics has been a long-standing research topic. Notably, the
antimicrobial peptides (AMPs) have been extensively studied for its therapeutic potential …

Background Microbial contamination in the global food industry, driven by the increasing
foodborne illness and food spoilage, brought the antimicrobial bioactive compounds into …

In his 1945 Nobel Prize acceptance speech, Sir Alexander Fleming warned of antimicrobial
resistance (AMR) if the necessary precautions were not taken diligently. As the growing …

Fungal contamination is among the leading causes of food spoilage promoting serious risks
to human health and economic losses. In 2021, 135 billion pounds of food, estimated at …

Motivation The widespread use of antibiotics has led to the emergence of resistant
pathogens. Antimicrobial peptides (AMPs) combat bacterial infections by disrupting the …