Periodontal inflammation and systemic diseases: an overview
Periodontitis is a common inflammatory disease of infectious origins that often evolves into a
chronic condition. Aside from its importance as a stomatologic ailment, chronic periodontitis …
chronic condition. Aside from its importance as a stomatologic ailment, chronic periodontitis …
From Infection to Immunity: Understanding the Response to SARS-CoV2 Through In-Silico Modeling
Background Immune system conditions of the patient is a key factor in COVID-19 infection
survival. A growing number of studies have focused on immunological determinants to …
survival. A growing number of studies have focused on immunological determinants to …
Toward mechanistic medical digital twins: some use cases in immunology
A fundamental challenge for personalized medicine is to capture enough of the complexity
of an individual patient to determine an optimal way to keep them healthy or restore their …
of an individual patient to determine an optimal way to keep them healthy or restore their …
Emulating complex simulations by machine learning methods
P Stolfi, F Castiglione - BMC bioinformatics, 2021 - Springer
Background The aim of the present paper is to construct an emulator of a complex biological
system simulator using a machine learning approach. More specifically, the simulator is a …
system simulator using a machine learning approach. More specifically, the simulator is a …
A multi-scale digital twin for adiposity-driven insulin resistance in humans: diet and drug effects
T Herrgårdh, C Simonsson, M Ekstedt… - Diabetology & Metabolic …, 2023 - Springer
Background The increased prevalence of insulin resistance is one of the major health risks
in society today. Insulin resistance involves both short-term dynamics, such as altered meal …
in society today. Insulin resistance involves both short-term dynamics, such as altered meal …
Influence of Sociodemographic Variables and Healthy Habits on the Values of Insulin Resistance Indicators in 386,924 Spanish Workers
M Mestre Font, C Busquets-Cortés, JI Ramírez-Manent… - Nutrients, 2023 - mdpi.com
Background: Insulin resistance (IR) is an alteration of the action of insulin in cells, which do
not respond adequately to this action, leading to an increase in blood glucose levels. IR …
not respond adequately to this action, leading to an increase in blood glucose levels. IR …
Potential predictors of type-2 diabetes risk: machine learning, synthetic data and wearable health devices
Background The aim of a recent research project was the investigation of the mechanisms
involved in the onset of type 2 diabetes in the absence of familiarity. This has led to the …
involved in the onset of type 2 diabetes in the absence of familiarity. This has led to the …
The Mechanism of Kelulut Honey in Reversing Metabolic Changes in Rats Fed with High-Carbohydrate High-Fat Diet
Metabolic syndrome (MetS) is composed of central obesity, hyperglycemia, dyslipidemia
and hypertension that increase an individual's tendency to develop type 2 diabetes mellitus …
and hypertension that increase an individual's tendency to develop type 2 diabetes mellitus …
African American females are less metabolically flexible compared with caucasian american females following a single high-fat meal: a pilot study
The relationship between metabolic flexibility (MF) and components of metabolic disease
has not been well-studied among African American (AA) females and may play a role in the …
has not been well-studied among African American (AA) females and may play a role in the …
Gut microbiome, COVID-19, and neurological impairment
R Das, R Singh, AK Tripathi - Gut Microbiome in Neurological Health and …, 2022 - Springer
The pandemic of COVID-19 caused by SARS-CoV-2 has created havoc worldwide. It causes
lung infection through binding of ACE2 receptors that are present on the alveolar epithelial …
lung infection through binding of ACE2 receptors that are present on the alveolar epithelial …