Bone remodeling is tightly controlled by osteoclast-mediated bone resorption and osteoblast-
mediated bone formation. Fine tuning of the osteoclast–osteoblast balance results in strict …

Abstract Interleukin (IL)-1β, a pro-inflammatory cytokine, was elevated and participates in
periodontitis. Not only the link between IL-1β and periodontitis was proved by clinical …

Background Nod‐like receptor family pyrin domain‐containing protein‐3 (NLRP3) complex
inflammasome has potentially been shown to play an important role in the development of …

Periodontal diseases (PD) are chronic infectious inflammatory diseases characterized by the
destruction of tooth-supporting structures, being the presence of periodontopathogens …

Inflammasomes are a group of multimolecular intracellular complexes assembled around
several innate immune proteins. Recognition of a diverse range of microbial, stress and …

Preshaw PM, Taylor JJ. How has research into cytokine interactions and their role in driving
immune responses impacted our understanding of periodontitis? J Clin Periodontol 2011; …

Inflammation is a pivotal response to a variety of stimuli, and inflammatory molecules such
as cytokines have central roles in the pathogenesis of various diseases, including bone and …

Background and Objective Peri‐implantitis is a destructive inflammatory process
characterized by destruction of the implant‐supporting bone. Inflammasomes are large …

Pyroptosis is a caspase-dependent process relevant to the understanding of beneficial host
responses and medical conditions for which inflammation is central to the pathophysiology …

Periodontitis is a chronic inflammatory disease that causes damage to periodontal tissues,
which include the gingiva, periodontal ligament, and alveolar bone. The major cause of …