A common feature of the hemodynamically or metabolically stressed heart is the return to a
pattern of fetal metabolism. A hallmark of fetal metabolism is the predominance of …

After myocardial infarction (MI), the heart undergoes extensive myocardial remodeling
through the accumulation of fibrous tissue in both the infarcted and noninfarcted …

Human-induced pluripotent stem cell-derived cardiomyocytes (hiPS-CMs) have been
recently derived and are used for basic research, cardiotoxicity assessment, and phenotypic …

Cardiovascular diseases are the leading cause of death worldwide. Heart failure is the
terminal manifestation of cardiovascular diseases, and its morbidity and mortality remain …

In humans, there is a significant decrease in serum T3 and increase in rT3 at different time
points after myocardial infarction, whereas serum TSH and T4 remain unaltered. We report …

Thyroid hormone (TH) is critical for tissue differentiation at early stages of development,
induces physiological hypertrophy and regulates the expression of important contractile …

Objective: Cardiac remodeling of viable myocardium occurs after acute myocardial infarction
(AMI) and further contributes to cardiac dysfunction. The present study explored whether …

Similarities in cardiac gene expression in hypothyroidism and left ventricular (LV)
pathological remodeling after myocardial infarction (MI) suggest a role for impaired cardiac …

Increased or reduced action of thyroid hormone on certain molecular pathways in the heart
and vasculature causes relevant cardiovascular derangements. It is well established that …

Many epidemiologic and animal studies have shown that maternal hypothyroidism is
associated with an increased risk of hypertension in offspring in later life. In this study, we …