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Treatment‐resistant depression: definition, prevalence, detection, management, and investigational interventions
Treatment‐resistant depression (TRD) is common and associated with multiple serious
public health implications. A consensus definition of TRD with demonstrated predictive utility …
public health implications. A consensus definition of TRD with demonstrated predictive utility …
Low-carbohydrate diet as a nutritional intervention in a major depression disorder: focus on relapse prevention
M Walaszek, Z Kachlik, WJ Cubała - Nutritional Neuroscience, 2024 - Taylor & Francis
Objectives: Mood disorders are trending to be among the leading causes of years lived with
disability. Despite multiple treatment options, around 30% patients with major depressive …
disability. Despite multiple treatment options, around 30% patients with major depressive …
[HTML][HTML] Immune-neuroendocrine crosstalk in mood and psychotic disorders: a meta-analysis and systematic review
M Van Den Noortgate, F Van Den Eede… - Brain, Behavior, & …, 2025 - Elsevier
Background Bidirectional interactions between immune and neuroendocrine mechanisms
are involved in mood and psychotic disorders, although individual studies report …
are involved in mood and psychotic disorders, although individual studies report …
Moderators of ayahuasca's biological antidepressant action
Introduction The understanding of biological responses to psychedelics with antidepressant
potential is imperative. Here we report how a set of acute parameters, namely emotional …
potential is imperative. Here we report how a set of acute parameters, namely emotional …
The plasma levels of 3-hydroxybutyrate, dityrosine, and other markers of oxidative stress and energy metabolism in major depressive disorder
Major depressive disorder (MDD) is a serious mental disease with a pathophysiology that is
not yet fully clarified. An increasing number of studies show an association of MDD with …
not yet fully clarified. An increasing number of studies show an association of MDD with …
The relationship between insomnia and the pathophysiology of major depressive disorder: an evaluation of a broad selection of serum and urine biomarkers
T Drinčić, JH van Dalfsen, J Kamphuis… - International journal of …, 2023 - mdpi.com
Insomnia exhibits a clinically relevant relationship with major depressive disorder (MDD).
Increasing evidence suggests that insomnia is associated with neurobiological alterations …
Increasing evidence suggests that insomnia is associated with neurobiological alterations …
[HTML][HTML] Impact of the COVID-19 pandemic on gender differences in depression based on national representative data
Background Restrictions on daily life and changes in economic structure due to coronavirus
disease 2019 (COVID-19) likely would have affected men and women differently. However …
disease 2019 (COVID-19) likely would have affected men and women differently. However …
Breathomics profiling of metabolic pathways affected by major depression: Possibilities and limitations
L Gbaoui, M Fachet, M Lüno, G Meyer-Lotz… - Frontiers in …, 2022 - frontiersin.org
Background Major depressive disorder (MDD) is one of the most common psychiatric
disorders with multifactorial etiologies. Metabolomics has recently emerged as a particularly …
disorders with multifactorial etiologies. Metabolomics has recently emerged as a particularly …
Interleukin-1β rs16944 and rs1143627 polymorphisms and risk of develo** major depressive disorder: A case-control study among Bangladeshi population
Background Epidemiological research suggests that altered levels of cytokine are
associated with pathophysiology and the development of major depressive disorder (MDD) …
associated with pathophysiology and the development of major depressive disorder (MDD) …
Low-carbohydrate diet as a disease modifier for relapse prevention of treatment-resistant depression. Spotlight on neuroplasticity and brain-derived neurotrophic …
Z Kachlik, M Walaszek, WJ Cubała - Medical Hypotheses, 2024 - Elsevier
Depression is the most common mental disorder with a high treatment resistance rate that
can affect patients at any age. Individuals who obtain insufficient and unsatisfactory …
can affect patients at any age. Individuals who obtain insufficient and unsatisfactory …