Nutrition and prevention of cognitive impairment

N Scarmeas, CA Anastasiou… - The Lancet Neurology, 2018 - thelancet.com
Nutrition is an important lifestyle factor that can modify the risk of future cognitive impairment
and dementia. Some, but not conclusive, evidence (mostly from observational studies and …

Glucose transporters in brain in health and disease

H Koepsell - Pflügers Archiv-European Journal of Physiology, 2020 - Springer
Energy demand of neurons in brain that is covered by glucose supply from the blood is
ensured by glucose transporters in capillaries and brain cells. In brain, the facilitative …

The impact of dietary macronutrient intake on cognitive function and the brain

AK Muth, SQ Park - Clinical Nutrition, 2021 - Elsevier
Macronutrients–carbohydrates, fats, and proteins–supply the nutrients required for optimal
functioning. Inadequate intake compromises both physical and brain health. We synthesized …

Interplay between the gut-brain axis, obesity and cognitive function

A Agustí, MP García-Pardo, I López-Almela… - Frontiers in …, 2018 - frontiersin.org
Obesity continues to be one of the major public health problems due to its high prevalence
and co-morbidities. Common co-morbidities not only include cardiometabolic disorders but …

The EAT–Lancet reference diet and cognitive function across the life course

B Dalile, C Kim, A Challinor, L Geurts… - The Lancet Planetary …, 2022 - thelancet.com
Summary The EAT–Lancet Commission devised a sustainable reference diet with the aim of
reducing the incidence of non-communicable diseases and mortality globally while …

Dimethyl itaconate ameliorates cognitive impairment induced by a high-fat diet via the gut-brain axis in mice

W Pan, J Zhao, J Wu, D Xu, X Meng, P Jiang, H Shi… - Microbiome, 2023 - Springer
Background Gut homeostasis, including intestinal immunity and microbiome, is essential for
cognitive function via the gut-brain axis. This axis is altered in high-fat diet (HFD)-induced …

Western diet consumption and cognitive impairment: links to hippocampal dysfunction and obesity

SE Kanoski, TL Davidson - Physiology & behavior, 2011 - Elsevier
Intake of saturated fats and simple carbohydrates, two of the primary components of a
modern Western diet, is linked with the development of obesity and Alzheimer's Disease …

Sex and gender driven modifiers of Alzheimer's: the role for estrogenic control across age, race, medical, and lifestyle risks

A Rahman, H Jackson, H Hristov… - Frontiers in aging …, 2019 - frontiersin.org
Research indicates that after advanced age, the major risk factor for late-onset Alzheimer's
disease (AD) is female sex. Out of every three AD patients, two are females with …

Systematic review: factors associated with risk for and possible prevention of cognitive decline in later life

BL Plassman, JW Williams Jr, JR Burke… - Annals of internal …, 2010 - acpjournals.org
Background: Many biological, behavioral, social, and environmental factors may contribute
to the delay or prevention of cognitive decline. Purpose: To summarize evidence about …

Damaging effects of a high-fat diet to the brain and cognition: a review of proposed mechanisms

LR Freeman, V Haley-Zitlin… - Nutritional …, 2014 - Taylor & Francis
The prevalence of obesity is growing and now includes at least one-third of the adult
population in the United States. As obesity and dementia rates reach epidemic proportions …