Invasive brain–machine interfaces can restore motor, sensory and cognitive functions.
However, their clinical adoption has been hindered by the surgical risk of implantation and …

Mitigating the foreign body response (FBR) to implantable medical devices (IMDs) is critical
for successful long‐term clinical deployment. The FBR is an inevitable immunological …

The aim of this review is to present a comprehensive overview of the feasibility of using
transparent neural interfaces in multimodal in vivo experiments on the central nervous …

Microglia are important players in surveillance and repair of the brain. Implanting an
electrode into the cortex activates microglia, produces an inflammatory cascade, triggers the …

Conducting polymers offer attractive mixed ionic-electronic conductivity, tunable interfacial
barrier with metal, tissue matchable softness, and versatile chemical functionalization …

Silicone elastomers, such as poly (dimethylsiloxane)(PDMS), have a broad range of
applications in basic biomedical research and clinical medicine, ranging from the …

Highlights•Bio-integrative strategies promote neural tissue-device integration.•Surface
modifications camouflage the surface and promote neuron attachment.•Drug delivery …

Seamless neural interfaces conjoining neurons and electrochemical devices hold great
potential for highly efficient signal transmission across neural systems and the external …

Neuroprosthetic devices that record and modulate neural activities have demonstrated
immense potential for bypassing or restoring lost neurological functions due to neural …

The brain is actuated by billions of neurons with trillions of interconnections that regulate
human behaviors. Understanding the mechanisms of these systems that induce sensory …