Tools for the analysis of high-dimensional single-cell RNA sequencing data

Y Wu, K Zhang - Nature Reviews Nephrology, 2020 - nature.com
Breakthroughs in the development of high-throughput technologies for profiling
transcriptomes at the single-cell level have helped biologists to understand the …

Visualizing and interpreting single-cell gene expression datasets with similarity weighted nonnegative embedding

Y Wu, P Tamayo, K Zhang - Cell systems, 2018 - cell.com
High-throughput single-cell gene expression profiling has enabled the definition of new cell
types and developmental trajectories. Visualizing these datasets is crucial to biological …

[KNIHA][B] Studying human development by single-cell profiling of primary human tissues and genetic perturbations of novel developmental models

Y Wu - 2020 - search.proquest.com
Understanding human development is critical to understanding human evolution, treating
developmental disorders, and creating regenerative therapeutics. Single-cell methods have …