Rehmapicroside ameliorates cerebral ischemia-reperfusion injury via attenuating peroxynitrite-mediated mitophagy activation

Y Zhang, Y He, M Wu, H Chen, L Zhang, D Yang… - Free Radical Biology …, 2020 - Elsevier
Abstract Peroxynitrite (ONOO−)-mediated mitophagy activation represents a vital pathogenic
mechanism in ischemic stroke. Our previous study suggests that ONOO− mediates Drp1 …

[HTML][HTML] Mitophagy antagonism by ZIKV reveals Ajuba as a regulator of PINK1 signaling, PKR-dependent inflammation, and viral invasion of tissues

SS Ponia, SJ Robertson, KL McNally, G Subramanian… - Cell Reports, 2021 - cell.com
Dysregulated inflammation dominated by chemokine expression is a key feature of disease
following infection with the globally important human pathogens Zika virus (ZIKV) and …

Positive regulation of human PINK1 and Parkin gene expression by nuclear respiratory factor 1

Y Lu, W Ding, B Wang, L Wang, H Kan, X Wang… - Mitochondrion, 2020 - Elsevier
Previous studies have demonstrated that two Parkinson's disease-associated genes PINK1
and Parkin play a key role in mitochondrial quality control. But until now, the transcriptional …

6‴-Feruloylspinosin alleviated beta-amyloid induced toxicity by promoting mitophagy in Caenorhabditis elegans (GMC101) and PC12 cells

T Yang, X Zhao, Y Zhang, J **e, A Zhou - Science of the Total Environment, 2020 - Elsevier
This study aims to investigate the neuroprotective effects of 6‴-feruloylspinosin (6-FS), one
of the main active flavonoid components in Sour Jujube seeds, on beta-amyloid (Aβ) protein …

Mitophagy induced by mitochondrial function damage in chicken kidney exposed to Cr (VI)

Y Wang, X Wang, L Wang, G Cheng, M Zhang… - … Trace Element Research, 2021 - Springer
Cr (VI) is a heavy metal environmental pollutant and carcinogen. Excessive Cr (VI) exposure
injures kidneys. This study aimed to investigate mitophagy induced by mitochondrial …

Age related immune modulation of experimental autoimmune encephalomyelitis in PINK1 knockout mice

D Cossu, K Yokoyama, S Sato, S Noda… - Frontiers in …, 2022 - frontiersin.org
Objective Recent research has shown that Parkin, an E3 ubiquitin ligase, modulates
peripheral immune cells-mediated immunity during experimental autoimmune …

Short overview

N Furuya - Mitophagy: Methods and Protocols, 2018 - Springer
Mitochondrial autophagy (mitophagy) is a mitochondrial quality control mechanism that
selectively removes damaged mitochondria via autophagic degradation. Autophagic …

Yellow Fever Virus Infection Alters Mitochondrial Network Dynamics

R Gomez, C Tomatis, M Scalise, P Thomas… - Authorea …, 2023 - advance.sagepub.com
In this work we studied the effect of Yellow Fever Virus (YFV) infection on mitochondrial
network dynamics (MD). Using the A549 cell line as a model, we examined MD during YFV …

Mitophagy antagonism by Zika virus reveals Ajuba as a regulator of PINK1-Parkin signaling, PKR-dependent inflammation, and viral invasion of tissues

SS Ponia, SJ Robertson, KL McNally, GL Sturdevant… - bioRxiv, 2021 - biorxiv.org
Dysregulated inflammation dominated by chemokine expression is a key feature of disease
following infection with the globally important human pathogens, Zika virus (ZIKV) and …

Yellow Fever Virus Infection Alters Mitochondrial Network Dynamics And Trigger Ifn-I Response Via Tlr2 Pathway

C Tomatis, N Charo, MF Ferrer, S Aquila… - Available at SSRN … - papers.ssrn.com
In recent decades, it has been emphasized that mitochondria play a fundamental role not
only in cellular bioenergetics but also in the defense against infections. Here, we …