Biosynthesis of fungal meroterpenoids
Covering: up to September 2015 Meroterpenoids are hybrid natural products that partially
originate from the terpenoid pathway. The meroterpenoids derived from fungi display quite …
originate from the terpenoid pathway. The meroterpenoids derived from fungi display quite …
Formation and cleavage of C–C bonds by enzymatic oxidation–reduction reactions
FP Guengerich, FK Yoshimoto - Chemical Reviews, 2018 - ACS Publications
Many oxidation–reduction (redox) enzymes, particularly oxygenases, have roles in reactions
that make and break C–C bonds. The list includes cytochrome P450 and other heme-based …
that make and break C–C bonds. The list includes cytochrome P450 and other heme-based …
HEx: A heterologous expression platform for the discovery of fungal natural products
CJB Harvey, M Tang, U Schlecht, J Horecka… - Science …, 2018 - science.org
For decades, fungi have been a source of US Food and Drug Administration–approved
natural products such as penicillin, cyclosporine, and the statins. Recent breakthroughs in …
natural products such as penicillin, cyclosporine, and the statins. Recent breakthroughs in …
Expansion of chemical space for natural products by uncommon P450 reactions
X Zhang, S Li - Natural product reports, 2017 - pubs.rsc.org
Covering: 2000 to 2017 Cytochrome P450 enzymes (P450s) are the most versatile
biocatalysts in nature. The catalytic competence of these extraordinary hemoproteins is …
biocatalysts in nature. The catalytic competence of these extraordinary hemoproteins is …
Versatile biocatalysis of fungal cytochrome P450 monooxygenases
Abstract Cytochrome P450 (CYP) monooxygenases, the nature's most versatile biological
catalysts have unique ability to catalyse regio-, chemo-, and stereospecific oxidation of a …
catalysts have unique ability to catalyse regio-, chemo-, and stereospecific oxidation of a …
Inclusion of terpenes in cyclodextrins: Preparation, characterization and pharmacological approaches
PSS Lima, AM Lucchese, HG Araujo-Filho… - Carbohydrate …, 2016 - Elsevier
Terpenes constitute the largest class of natural products and are important resources for the
pharmaceutical, food and cosmetics industries. However, due to their low water solubility …
pharmaceutical, food and cosmetics industries. However, due to their low water solubility …
Recent developments in self-resistance gene directed natural product discovery
Covering: 2000 to 2019 Natural products (NPs) are important sources of human therapeutic
agents and pesticides. To prevent self-harm from bioactive NPs, some microbial producers …
agents and pesticides. To prevent self-harm from bioactive NPs, some microbial producers …
Substrate oxidation by cytochrome P450 enzymes
PR Ortiz de Montellano - Cytochrome P450: structure, mechanism, and …, 2015 - Springer
Cytochrome P450 enzymes catalyze a broad diversity of reactions, including well-
established transformations such as carbon and nitrogen hydroxylation, heteroatom …
established transformations such as carbon and nitrogen hydroxylation, heteroatom …
Detecting and prioritizing biosynthetic gene clusters for bioactive compounds in bacteria and fungi
Secondary metabolites (SM) produced by fungi and bacteria have long been of exceptional
interest owing to their unique biomedical ramifications. The traditional discovery of new …
interest owing to their unique biomedical ramifications. The traditional discovery of new …
Biosynthesis of fungal terpenoids
P Luo, JH Huang, JM Lv, GQ Wang, D Hu… - Natural Product …, 2024 - pubs.rsc.org
Covering: up to August 2023Terpenoids, which are widely distributed in animals, plants, and
microorganisms, are a large group of natural products with diverse structures and various …
microorganisms, are a large group of natural products with diverse structures and various …