Regulation of SIRT1 and its roles in inflammation

Y Yang, Y Liu, Y Wang, Y Chao, J Zhang, Y Jia… - Frontiers in …, 2022 - frontiersin.org
The silent information regulator sirtuin 1 (SIRT1) protein, a highly conserved NAD+-
dependent deacetylase belonging to the sirtuin family, is a post-translational regulator that …

Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders

A Kauppinen, T Suuronen, J Ojala, K Kaarniranta… - Cellular signalling, 2013 - Elsevier
Recent studies have indicated that the regulation of innate immunity and energy metabolism
are connected together through an antagonistic crosstalk between NF-κB and SIRT1 …

Stem cells and the impact of ROS signaling

CL Bigarella, R Liang, S Ghaffari - Development, 2014 - journals.biologists.com
An appropriate balance between self-renewal and differentiation is crucial for stem cell
function during both early development and tissue homeostasis throughout life. Recent …

Effects of sex, strain, and energy intake on hallmarks of aging in mice

SJ Mitchell, J Madrigal-Matute, M Scheibye-Knudsen… - Cell metabolism, 2016 - cell.com
Calorie restriction (CR) is the most robust non-genetic intervention to delay aging. However,
there are a number of emerging experimental variables that alter CR responses. We …

Redox regulation of SIRT1 in inflammation and cellular senescence

J Hwang, H Yao, S Caito, IK Sundar… - Free Radical Biology and …, 2013 - Elsevier
Sirtuin 1 (SIRT1) regulates inflammation, aging (life span and health span), calorie
restriction/energetics, mitochondrial biogenesis, stress resistance, cellular senescence …

Redox signaling in cardiac physiology and pathology

JR Burgoyne, H Mongue-Din, P Eaton… - Circulation …, 2012 - Am Heart Assoc
Redox signaling refers to the specific and usually reversible oxidation/reduction modification
of molecules involved in cellular signaling pathways. In the heart, redox signaling regulates …

Crosstalk between oxidative stress and SIRT1: impact on the aging process

A Salminen, K Kaarniranta, A Kauppinen - International journal of …, 2013 - mdpi.com
Increased oxidative stress has been associated with the aging process. However, recent
studies have revealed that a low-level oxidative stress can even extend the lifespan of …

[BOOK][B] Chemical reagents for protein modification

RL Lundblad - 2004 - taylorfrancis.com
Revised and updated, Chemical Reagents for Protein Modification, Third Edition is an
encyclopedic work describing the many approaches to the site-specific modification of …

eNOS uncoupling in cardiovascular diseases-the role of oxidative stress and inflammation

S Karbach, P Wenzel, A Waisman… - Current …, 2014 - ingentaconnect.com
Many cardiovascular diseases and drug-induced complications are associated with-or even
based on-an imbalance between the formation of reactive oxygen and nitrogen species …

Banting lecture 2011: hyperinsulinemia: cause or consequence?

BE Corkey - Diabetes, 2012 - Am Diabetes Assoc
The Banting Medal for Scientific Achievement Award is the American Diabetes Association's
highest scientific award and honors an individual who has made significant, long-term …