Defining trained immunity and its role in health and disease
Immune memory is a defining feature of the acquired immune system, but activation of the
innate immune system can also result in enhanced responsiveness to subsequent triggers …
innate immune system can also result in enhanced responsiveness to subsequent triggers …
Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?
SE Engelen, AJB Robinson, YX Zurke… - Nature Reviews …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall, characterized by the
formation of plaques containing lipid, connective tissue and immune cells in the intima of …
formation of plaques containing lipid, connective tissue and immune cells in the intima of …
[HTML][HTML] Western diet and the immune system: an inflammatory connection
A Christ, M Lauterbach, E Latz - Immunity, 2019 - cell.com
The consumption of Western-type calorically rich diets combined with chronic overnutrition
and a sedentary lifestyle in Western societies evokes a state of chronic metabolic …
and a sedentary lifestyle in Western societies evokes a state of chronic metabolic …
Innate and adaptive immune memory: an evolutionary continuum in the host's response to pathogens
Immunological memory is an important evolutionary trait that improves host survival upon
reinfection. Memory is a characteristic recognized within both the innate and adaptive arms …
reinfection. Memory is a characteristic recognized within both the innate and adaptive arms …
Trained immunity: adaptation within innate immune mechanisms
J Domínguez-Andrés, JC Dos Santos… - Physiological …, 2023 - journals.physiology.org
The mechanisms underlying innate immune memory have been extensively explored in the
last decades but are in fact largely unknown. Although the specificity of adaptive immune …
last decades but are in fact largely unknown. Although the specificity of adaptive immune …
Induction of autonomous memory alveolar macrophages requires T cell help and is critical to trained immunity
Innate immune memory is an emerging area of research. However, innate immune memory
at major mucosal sites remains poorly understood. Here, we show that respiratory viral …
at major mucosal sites remains poorly understood. Here, we show that respiratory viral …
Antimicrobial peptides: mechanism of action, activity and clinical potential
QY Zhang, ZB Yan, YM Meng, XY Hong, G Shao… - Military Medical …, 2021 - Springer
The management of bacterial infections is becoming a major clinical challenge due to the
rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome …
rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome …
The coral microbiome: towards an understanding of the molecular mechanisms of coral–microbiota interactions
Corals live in a complex, multipartite symbiosis with diverse microbes across kingdoms,
some of which are implicated in vital functions, such as those related to resilience against …
some of which are implicated in vital functions, such as those related to resilience against …
Potential role of gut microbiota in induction and regulation of innate immune memory
The gut microbiota significantly regulates the development and function of the innate and
adaptive immune system. The attribute of immunological memory has long been linked only …
adaptive immune system. The attribute of immunological memory has long been linked only …
Human health in relation to exposure to solar ultraviolet radiation under changing stratospheric ozone and climate
RM Lucas, S Yazar, AR Young, M Norval… - Photochemical & …, 2019 - pubs.rsc.org
The Montreal Protocol has limited increases in the UV-B (280–315 nm) radiation reaching
the Earth's surface as a result of depletion of stratospheric ozone. Nevertheless, the …
the Earth's surface as a result of depletion of stratospheric ozone. Nevertheless, the …