Nanotechnology applied to the treatment of malaria

NS Santos-Magalhães, VCF Mosqueira - Advanced drug delivery reviews, 2010 - Elsevier
Despite the fact that we live in an era of advanced technology and innovation, infectious
diseases, like malaria, continue to be one of the greatest health challenges worldwide. The …

Smart drug-delivery systems for cancer nanotherapy

P Sanchez-Moreno, JL Ortega-Vinuesa… - Current drug …, 2018 - ingentaconnect.com
Background: Despite all the advances achieved in the field of tumor-biology research, in
most cases conventional therapies including chemotherapy are still the leading choices. The …

[BUCH][B] Drug delivery systems

VV Ranade, MA Hollinger, JB Cannon - 2003 - taylorfrancis.com
Drug delivery technologies represent a vast and vital area of Research and Development.
The demand for innovative drug delivery systems continues to grow, and this growth …

Polyethylene Glycol Conjugated Polymeric Nanocapsules for Targeted Delivery of Quercetin to Folate-Expressing Cancer Cells in Vitro and in Vivo

RI El-Gogary, N Rubio, JTW Wang, WT Al-Jamal… - ACS …, 2014 - ACS Publications
In this work we describe the formulation and characterization of chemically modified
polymeric nanocapsules incorporating the anticancer drug, quercetin, for the passive and …

Release profiles and morphological characterization by atomic force microscopy and photon correlation spectroscopy of 99mTechnetium-fluconazole nanocapsules

DN de Assis, VCF Mosqueira, JMC Vilela… - International journal of …, 2008 - Elsevier
Several classes of antifungal have been employed in candidiasis treatment, but patients with
advanced immunodeficiency can present unsatisfactory results after therapy. In these cases …

PEGylated and functionalized polylactide-based nanocapsules: An overview

MA de Oliveira, RS Araújo, VCF Mosqueira - International Journal of …, 2023 - Elsevier
Polymeric nanocapsules (NC) are versatile mixed vesicular nanocarriers, generally
containing a lipid core with a polymeric wall. They have been first developed over four …

Porphyrin derivative nanoformulations for therapy and antiparasitic agents

DK Deda, BA Iglesias, E Alves, K Araki, CRS Garcia - Molecules, 2020 - mdpi.com
Porphyrins and analogous macrocycles exhibit interesting photochemical, catalytic, and
luminescence properties demonstrating high potential in the treatment of several diseases …

Cardiotoxicity reduction induced by halofantrine entrapped in nanocapsule devices

EA Leite, A Grabe-Guimarães, HN Guimarães… - Life sciences, 2007 - Elsevier
The main objective of the present study was to evaluate the reduction in halofantrine (Hf)
toxicity, an antimalarial drug frequently associated with QT interval prolongation in …

Mechanisms of interaction of biodegradable polyester nanocapsules with non-phagocytic cells

IC Trindade, G Pound-Lana, DGS Pereira… - European Journal of …, 2018 - Elsevier
The interaction of polymer nanocapsules (NC) prepared from four biodegradable polyesters
with variable polymer hydrophobicity (PCL, PLA, PLGA and PLA-PEG) was investigated in …

Characterization of different functionalized lipidic nanocapsules as potential drug carriers

P Sánchez-Moreno, JL Ortega-Vinuesa… - International journal of …, 2012 - mdpi.com
Lipid nanocapsules (LNC) based on a core-shell structure consisting of an oil-filled core with
a surrounding polymer layer are known to be promising vehicles for the delivery of …