Reactive oxygen species (ROS)-responsive biomaterials mediate tissue microenvironments and tissue regeneration

Y Yao, H Zhang, Z Wang, J Ding, S Wang… - Journal of Materials …, 2019 - pubs.rsc.org
Reactive oxygen species (ROS) have been considered the pivotal signaling molecules in
many physiological processes, and are usually overproduced in various inflammatory …

Nanotechnology for cardiovascular diseases

Q Hu, Z Fang, J Ge, H Li - The Innovation, 2022 - cell.com
Cardiovascular diseases have become the major killers in today's world, among which
coronary artery diseases (CADs) make the greatest contributions to morbidity and mortality …

Smart liposomal nanocarrier enhanced the treatment of ischemic stroke through neutrophil extracellular traps and cyclic guanosine monophosphate-adenosine …

S Sun, W Lv, S Li, Q Zhang, W He, Z Min, C Teng… - ACS …, 2023 - ACS Publications
Brain inflammation is regarded as one of the leading causes that aggravates secondary
brain injury and hinders the prognosis of ischemic stroke. After ischemic stroke, high …

Bioresponsive drug delivery systems for the treatment of inflammatory diseases

Y Dou, C Li, L Li, J Guo, J Zhang - Journal of Controlled Release, 2020 - Elsevier
Inflammation is intimately related to the pathogenesis of numerous acute and chronic
diseases like cardiovascular disease, inflammatory bowel disease, rheumatoid arthritis, and …

Nanomaterials for nanotheranostics: tuning their properties according to disease needs

XY Wong, A Sena-Torralba, R Alvarez-Diduk… - ACS …, 2020 - ACS Publications
Nanotheranostics is one of the biggest scientific breakthroughs in nanomedicine. Most of the
currently available diagnosis and therapies are invasive, time-consuming, and associated …

Microthrombus‐targeting micelles for neurovascular remodeling and enhanced microcirculatory perfusion in acute ischemic stroke

Y Lu, C Li, Q Chen, P Liu, Q Guo, Y Zhang… - Advanced …, 2019 - Wiley Online Library
Reperfusion injury exists as the major obstacle to full recovery of neuron functions after
ischemic stroke onset and clinical thrombolytic therapies. Complex cellular cascades …

Elaborately engineering a self‐Indicating dual‐drug nanoassembly for site‐specific photothermal‐potentiated thrombus penetration and thrombolysis

Z Zhao, X Zhang, H Zhang, X Shan, M Bai… - Advanced …, 2022 - Wiley Online Library
Thrombotic cardio‐cerebrovascular diseases seriously threaten human health. Currently,
conventional thrombolytic treatments are challenged by the low utilization, inferior thrombus …

Construction of intelligent moving micro/nanomotors and their applications in biosensing and disease treatment

Y Guo, D **g, S Liu, Q Yuan - Theranostics, 2023 - pmc.ncbi.nlm.nih.gov
Micro/nanomotors are containers that pass through liquid media and carry cargo. Because
they are tiny, micro/nanomotors exhibit excellent potential for biosensing and disease …

Advanced drug delivery system against ischemic stroke

S Zhang, Y Zhou, R Li, Z Chen, X Fan - Journal of Controlled Release, 2022 - Elsevier
Ischemic stroke is a vascular central nervous system (CNS) disease that leads a disability
and death. Thrombolysis and neuroprotection are the primary treatment strategies of …

Biomimetic fibrin-targeted and H2O2-responsive nanocarriers for thrombus therapy

Y Zhao, R **e, N Yodsanit, M Ye, Y Wang, S Gong - Nano Today, 2020 - Elsevier
Thrombosis is a principle cause of various life-threatening cardiovascular diseases.
However, current antithrombotic treatments using drugs only offer limited efficacy due to …