Biological properties of extracellular vesicles and their physiological functions

M Yáñez-Mó, PRM Siljander, Z Andreu… - Journal of …, 2015 - Taylor & Francis
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …

[HTML][HTML] Extracellular vesicles—connecting kingdoms

E Woith, G Fuhrmann, MF Melzig - International journal of molecular …, 2019 - mdpi.com
It is known that extracellular vesicles (EVs) are shed from cells of almost every type of cell or
organism, showing their ubiquity in all empires of life. EVs are defined as naturally released …

Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity

AH Buck, G Coakley, F Simbari, HJ McSorley… - Nature …, 2014 - nature.com
In mammalian systems RNA can move between cells via vesicles. Here we demonstrate that
the gastrointestinal nematode Heligmosomoides polygyrus, which infects mice, secretes …

Exosomes and other extracellular vesicles: the new communicators in parasite infections

G Coakley, RM Maizels, AH Buck - Trends in parasitology, 2015 - cell.com
Extracellular vesicles (EVs) have emerged as a ubiquitous mechanism for transferring
information between cells and organisms across all three kingdoms of life. In addition to their …

Guidelines for the purification and characterization of extracellular vesicles of parasites

C Fernandez‐Becerra, P Xander… - Journal of …, 2023 - Wiley Online Library
Parasites are responsible for the most neglected tropical diseases, affecting over a billion
people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible …

Extracellular vesicles in parasitic diseases

A Marcilla, L Martin-Jaular, M Trelis… - Journal of …, 2014 - Taylor & Francis
Parasitic diseases affect billions of people and are considered a major public health issue.
Close to 400 species are estimated to parasitize humans, of which around 90 are …

sRNAtoolbox: an integrated collection of small RNA research tools

A Rueda, G Barturen, R Lebrón… - Nucleic acids …, 2015 - academic.oup.com
Small RNA research is a rapidly growing field. Apart from microRNAs, which are important
regulators of gene expression, other types of functional small RNA molecules have been …

Release of Small RNA-containing Exosome-like Vesicles from the Human Filarial Parasite Brugia malayi

M Zamanian, LM Fraser, PN Agbedanu… - PLoS neglected …, 2015 - journals.plos.org
Lymphatic filariasis (LF) is a socio-economically devastating mosquito-borne Neglected
Tropical Disease caused by parasitic filarial nematodes. The interaction between the …

[HTML][HTML] The protein and microRNA cargo of extracellular vesicles from parasitic helminths–current status and research priorities

J Sotillo, MW Robinson, MJ Kimber, M Cucher… - International journal for …, 2020 - Elsevier
Helminth parasites have a remarkable ability to persist within their mammalian hosts, which
is largely due to their secretion of molecules with immunomodulatory properties. Although …

Carcinogenic liver fluke secretes extracellular vesicles that promote cholangiocytes to adopt a tumorigenic phenotype

S Chaiyadet, J Sotillo, M Smout… - The Journal of …, 2015 - academic.oup.com
Abstract Background. Throughout Asia, there is an unprecedented link between
cholangiocarcinoma and infection with the liver fluke Opisthorchis viverrini. Multiple …