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Therapeutic strategies for COVID-19: progress and lessons learned
G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
SARS-CoV-2 variant biology: immune escape, transmission and fitness
In late 2020, after circulating for almost a year in the human population, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …
Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting
The continuing emergence of SARS-CoV-2 variants highlights the need to update COVID-19
vaccine compositions. However, immune imprinting induced by vaccination based on the …
vaccine compositions. However, immune imprinting induced by vaccination based on the …
Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution
Continuous evolution of Omicron has led to a rapid and simultaneous emergence of
numerous variants that display growth advantages over BA. 5 (ref.). Despite their divergent …
numerous variants that display growth advantages over BA. 5 (ref.). Despite their divergent …
FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2
Preventing SARS-CoV-2 infection by modulating viral host receptors, such as angiotensin-
converting enzyme 2 (ACE2), could represent a new chemoprophylactic approach for …
converting enzyme 2 (ACE2), could represent a new chemoprophylactic approach for …
A detailed overview of SARS-CoV-2 omicron: its sub-variants, mutations and pathophysiology, clinical characteristics, immunological landscape, immune escape, and …
The COVID-19 pandemic has created significant concern for everyone. Recent data from
many worldwide reports suggest that most infections are caused by the Omicron variant and …
many worldwide reports suggest that most infections are caused by the Omicron variant and …
[HTML][HTML] Enhanced neutralization resistance of SARS-CoV-2 omicron subvariants BQ. 1, BQ. 1.1, BA. 4.6, BF. 7, and BA. 2.75. 2
P Qu, JP Evans, JN Faraone, YM Zheng, C Carlin… - Cell host & …, 2023 - cell.com
The continued evolution of SARS-CoV-2 has led to the emergence of several new Omicron
subvariants, including BQ. 1, BQ. 1.1, BA. 4.6, BF. 7, and BA. 2.75. 2. Here, we examine the …
subvariants, including BQ. 1, BQ. 1.1, BA. 4.6, BF. 7, and BA. 2.75. 2. Here, we examine the …
VV116 versus nirmatrelvir–ritonavir for oral treatment of Covid-19
Z Cao, W Gao, H Bao, H Feng, S Mei… - … England Journal of …, 2023 - Mass Medical Soc
Background Nirmatrelvir–ritonavir has been authorized for emergency use by many
countries for the treatment of coronavirus disease 2019 (Covid-19). However, the supply …
countries for the treatment of coronavirus disease 2019 (Covid-19). However, the supply …
BA. 2.12. 1, BA. 4 and BA. 5 escape antibodies elicited by Omicron infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages BA.
2.12. 1, BA. 4 and BA. 5 exhibit higher transmissibility than the BA. 2 lineage. The receptor …
2.12. 1, BA. 4 and BA. 5 exhibit higher transmissibility than the BA. 2 lineage. The receptor …
Incubation period of COVID-19 caused by unique SARS-CoV-2 strains: a systematic review and meta-analysis
Importance Several studies were conducted to estimate the average incubation period of
COVID-19; however, the incubation period of COVID-19 caused by different SARS-CoV-2 …
COVID-19; however, the incubation period of COVID-19 caused by different SARS-CoV-2 …