Brain metastases are a serious obstacle in the treatment of patients with solid tumors and
contribute to the morbidity and mortality of these cancers. It is speculated that the frequency …

Learning Objectives After completing this course, the reader will be able to: Identify the
clinical factors that predict survival after a diagnosis of brain metastasis. Select appropriate …

Background It is unclear whether the benefit of adding whole-brain radiation therapy
(WBRT) to stereotactic radiosurgery (SRS) for the control of brain-tumours outweighs the …

PURPOSE: Controversy endures regarding the optimal treatment of patients with brain
metastases (BMs). Debate persists, despite many randomized trials, perhaps because BM …

Abstract The Montreal Cognitive Assessment (MoCA) is a cognitive screening instrument
developed to detect mild cognitive impairment (MCI). It is a simple 10 min paper and pencil …

A 50-year-old man with a history of lung cancer presents with headaches and right-arm
numbness; he is found to have a single brain metastasis. Stereotactic radiosurgery is …

Purpose To identify an optimal margin about the gross target volume (GTV) for stereotactic
radiosurgery (SRS) of brain metastases, minimizing toxicity and local recurrence. Methods …

PURPOSE: To prospectively compare the effect of prophylactic and therapeutic whole brain
radiotherapy (WBRT) on memory function in patients with and without brain metastases …

Stereotactic radiosurgery (SRS) was developed decades ago but only began to impact brain
tumor care when it was coupled with high-resolution brain imaging techniques such as …

Many questions need future trials: the usefulness of new radiosensitizers; the role of local
treatments after surgery; and the impact of molecularly targeted therapies on subgroups of …