[HTML][HTML] Gram-positive bacterial cell envelopes: The impact on the activity of antimicrobial peptides
N Malanovic, K Lohner - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
A number of cationic antimicrobial peptides, effectors of innate immunity, are supposed to
act at the cytoplasmic membrane leading to permeabilization and eventually membrane …
act at the cytoplasmic membrane leading to permeabilization and eventually membrane …
Antimicrobial peptides targeting gram-positive bacteria
N Malanovic, K Lohner - Pharmaceuticals, 2016 - mdpi.com
Antimicrobial peptides (AMPs) have remarkably different structures as well as biological
activity profiles, whereupon most of these peptides are supposed to kill bacteria via …
activity profiles, whereupon most of these peptides are supposed to kill bacteria via …
The immune response to infection in the bladder
L Lacerda Mariano, MA Ingersoll - Nature Reviews Urology, 2020 - nature.com
The bladder is continuously protected by passive defences such as a mucus layer,
antimicrobial peptides and secretory immunoglobulins; however, these defences are …
antimicrobial peptides and secretory immunoglobulins; however, these defences are …
[HTML][HTML] TLR8 is a sensor of RNase T2 degradation products
TLR8 is among the highest-expressed pattern-recognition receptors in the human myeloid
compartment, yet its mode of action is poorly understood. TLR8 engages two distinct ligand …
compartment, yet its mode of action is poorly understood. TLR8 engages two distinct ligand …
Immune modulation by human secreted RNases at the extracellular space
The ribonuclease A superfamily is a vertebrate-specific family of proteins that encompasses
eight functional members in humans. The proteins are secreted by diverse innate immune …
eight functional members in humans. The proteins are secreted by diverse innate immune …
Friends or Foes? Host defense (antimicrobial) peptides and proteins in human skin diseases
F Niyonsaba, C Kiatsurayanon… - Experimental …, 2017 - Wiley Online Library
Host defense peptides/proteins (HDP s), also known as antimicrobial peptides/proteins
(AMP s), are key molecules in the cutaneous innate immune system. AMP s/HDP s …
(AMP s), are key molecules in the cutaneous innate immune system. AMP s/HDP s …
[HTML][HTML] Novel targets to develop new antibacterial agents and novel alternatives to antibacterial agents
TM Belete - Human Microbiome Journal, 2019 - Elsevier
Antibacterial agents have saved many lives and helped the growth of modern medicine over
the past half century. The emergence of drug resistance, jeopardizing the effectiveness of …
the past half century. The emergence of drug resistance, jeopardizing the effectiveness of …
The innate immune response during urinary tract infection and pyelonephritis
Despite its proximity to the fecal flora, the urinary tract is considered sterile. The precise
mechanisms by which the urinary tract maintains sterility are not well understood. Host …
mechanisms by which the urinary tract maintains sterility are not well understood. Host …
The ribonuclease a superfamily in humans: canonical RNases as the buttress of innate immunity
P Koczera, L Martin, G Marx, T Schuerholz - International journal of …, 2016 - mdpi.com
In humans, the ribonuclease A (RNase A) superfamily contains eight different members that
have RNase activities, and all of these members are encoded on chromosome 14. The …
have RNase activities, and all of these members are encoded on chromosome 14. The …
[HTML][HTML] The eight human “canonical” ribonucleases: molecular diversity, catalytic properties, and special biological actions of the enzyme proteins
S Sorrentino - FEBS letters, 2010 - Elsevier
Human ribonucleases (RNases) are members of a large superfamily of rapidly evolving
homologous proteins. Upon completion of the human genome, eight catalytically active …
homologous proteins. Upon completion of the human genome, eight catalytically active …