It has been known for 80years that cancer cell growth in an energy-related process
supported by an increased glucose metabolism. This phenomenon suggests a need for a …

Glycolysis is a tightly regulated process in which several enzymes, such as Hexokinases
(HKs), play crucial roles. Cancer cells are characterized by specific expression levels of …

Fever of unknown origin (FUO) was originally defined as recurrent fever of 38.3° C or higher,
lasting 2–3 wk or longer, and undiagnosed after 1 wk of hospital evaluation. The last …

Tuberculosis is classically divided into states of latent infection and active disease. Using
combined positron emission and computed tomography in 35 asymptomatic, antiretroviral …

The diagnostic definition of indeterminate lung nodules as malignant or benign poses a
major challenge for clinicians. We discovered a potential marker, the sodium-dependent …

Metabolism encompasses the biochemical processes that allow healthy cells to keep
energy, redox balance and building blocks required for cell development, survival, and …

Glucose, a major source of energy for all cells, is transported into cells with the help of
glucose transporters (GLUTs). These transporters are of two types, namely sodium …

This overview of the oncologic applications of positron emission tomography (PET) focuses
on the technical aspects and clinical applications of a newer technique: the combination of a …

Importance Positron emission tomography (PET) combined with fludeoxyglucose F 18 (FDG)
is recommended for the noninvasive diagnosis of pulmonary nodules suspicious for lung …

Applying basic biochemical principles, this review analyzes data that contrasts with the
Warburg hypothesis that glycolysis is the exclusive ATP provider in cancer cells. Although …