Bacterial plasmids encode partitioning (par) loci that ensure ordered plasmid segregation
prior to cell division. par loci come in two types: those that encode actin-like ATPases and …

Plasmids are ubiquitous in the microbial world and have been identified in almost all
species of bacteria that have been examined. Their localization inside the bacterial cell has …

Liquid-liquid phase-separated (LLPS) states are key to compartmentalizing components in
the absence of membranes; however, it is unclear whether LLPS condensates are actively …

The faithful segregation of duplicated genetic material into daughter cells is critical to all
organisms. In many bacteria, the segregation of chromosomes involves transport of …

Cells rely on the precise action of proteins that detect and repair DNA damage. However,
gene expression noise causes fluctuations in protein abundances that may compromise …

Many canonical processes in molecular biology rely on the dynamic assembly of higher-
order nucleoprotein complexes. In bacteria, the assembly mechanism of ParABS, the …

Increasingly diverse types of cargo are being found to be segregated and positioned by
ParA-type ATPases. Several minimalistic systems described in bacteria are self-organizing …

Chromosome and plasmid segregation in bacteria are mostly driven by ParAB S systems.
These DNA partitioning machineries rely on large nucleoprotein complexes assembled on …

Bacterial plasmids are extrachromosomal DNA that provides selective advantages for
bacterial survival. Plasmid partitioning can be remarkably robust. For high-copy-number …

In bacteria, mitotic stability of plasmids and many chromosomes depends on replicon‐
specific systems which comprise a centromere, a centromere‐binding protein and an …