Human cancers represent complex structures, which display substantial inter-and intratumor
heterogeneity in their genetic expression and phenotypic features. However, cancers …

Quantitative imaging is the analysis of retrieved numeric data from images with the goal of
reducing subjective assessment. It is an increasingly important radiologic tool to assess …

We aim to review the technique and clinical applications of perfusion CT (PCT) of head and
neck cancer. The clinical value of PCT in the head and neck includes detection of head and …

In the genomics era, our main goal should be to identify large and meaningful differences in
small, molecularly selected groups of patients. Classical phase I, II and III models for drug …

Purpose Multiple imaging techniques are nowadays available for clinical in-vivo
visualization of tumour biology. FDG PET/CT identifies increased tumour metabolism …

Purpose Evaluation of perfusion CT and dual-energy CT (DECT) quantitative parameters for
predicting microvascular invasion (MVI) of hepatocellular carcinoma (HCC) prior to surgery …

Objectives To investigate the potential contribution of iodine uptake calculation from dual-
phase dual-energy CT (DE-CT) for lymph node staging and therapy response monitoring in …

Hostile microenvironment produced by abnormal blood vessels, which is characterized by
hypoxia, low pH value and increasing interstitial fluid pressure, would facilitate tumor …

Twenty years ago, theoretical developments were initiated to model the behavior of the NMR
transverse relaxation rates in presence of vessels. These developments enabled the MRI …

Ongoing research on malignant and normal cell biology has substantially enhanced the
understanding of the biology of cancer and carcinogenesis. This has led to the development …